Prefilled Syringes- Insights into Novel Drug Delivery System

Prefilled Syringes- Insights into Novel Drug Delivery System

Prefilled Syringes
The global prefilled syringes market was valued at US$ 2,805.4 million in 2015 and is expected to witness a CAGR of 11% during the forecast period (2017 – 2025).

The prefilled syringes are one of the fastest growing choices for the unit dose delivery and has emerged as one of the most convenient way of drug delivery method in the recent years. The extensive use of prefilled syringes has enabled the pharmaceutical companies to minimize drug-wastage and increase the life-span of the product at the same time. The plastic disposable syringes has created a revolution in the healthcare market which has been enhanced by the introduction of sterile prefilled syringes that enables safe self-administration of injectable drugs to patients sitting at home without a need to visit hospitals. According to National Center for Biotechnology Information (NCBI), 25% of expenditure on drugs goes unused and wasted in the United States while 3-7% of medications intended towards patients goes unused. These massive revenues could be directed in a useful way with the use of prefilled syringes in the market that enables to improve the shelf life of the drugs as well as avoids wastage of drugs as the syringes are filled with exact volume and concentration of the drug that will deliver optimum results. Prefilled syringes make a profitable deal for the pharmaceutical companies too, as these companies can be benefitted from the less over-fill of drugs as compared to the vials that serves to be an important advantage, particularly in case of costly biopharmaceuticals.

The global prefilled syringes market was valued at US$ 2,805.4 million in 2015 and is expected to witness a CAGR of 11% during the forecast period (2017 – 2025).

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Key features of the study:

  • This report provides in-depth analysis of the prefilled syringes market and its application, market size (US$ Million) and Cumulative Annual Growth Rate (CAGR (%)) for the forecast period: 2017 – 2025, considering 2017 as the base year.
  • It elucidates potential revenue opportunity across different segments and explains attractive investment proposition matrix for this market.
  • This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, regional outlook, and competitive strategy adopted by the leading players.
  • It profiles leading players in the global prefilled syringes market based on the following parameters – company overview, financial performance, product portfolio, geographical presence, distribution strategies, key developments and strategies and future plans.
  • Key companies covered as a part of this study include Becton Dickinson & Co., Gerresheimer, Medtronic, Baxter International, SCHOTT AG, West Pharmaceuticals, Vetter International, Unilife Corporation, Stevanato Group and Terumo Corporation.
  • Insights from this report would allow marketers and management authorities of companies to make informed decision with respect to their future product launch, end user upgrades, market expansion and marketing tactics.
  • The global prefilled syringes market report caters to various stakeholders in this industry, including investors, product manufacturers, distributors and suppliers for prefilled syringes market, research and consulting firms, new entrants and financial analysts
  • Various strategy matrices used in analyzing the prefilled syringes market would provide stakeholders vital inputs to make strategic decisions accordingly

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Rise in prevalence of chronic diseases globally augments the market growth of the prefilled syringes

Chronic diseases such as type 1 diabetes is encountered among a significant population across the globe, wherein the patients are suggested to undergo regular intra-venous administration of insulin to control their sugar levels inability in natural insulin production. These injections are easy and feasible task with the use of pre-filled syringes that makes the self-administration more convenient and viable. According to Centers for Disease Control and Prevention (CDC), 2014, around 29.1 million people in the U.S. were suffering from diabetes, accounting for 9.3% of the total population. These figures suggests need for the development in the technology for the cure and prevention of the diseases. The North American market shows significant growth in the adaption of technological advancements such as prefilled syringes that helps in the treatment of diseases with precision, affordability and easy techniques that promotes the use of self-medication. On the other hand, various alternative techniques prevailing in the market for drug administration such as transdermal delivery systems that facilitates pain-free administration of drugs can hamper to the growth of the prefilled syringes market to a certain extend. Furthermore, the drug interaction with the packaging material leading to chemical reaction that may change the effectivity and impact of the drug on the patient marks as one of the serious issue restraining the market growth as these chemicals can prove fatal at certain point of times. However, key players operating the prefilled syringes market are engaged in research activities to come up with packaging material that will not interfere in the composition of the drug dosage.

Key players indulged in strategic implementation of various policies for the stabilization of prefilled syringes as well as to encounter other issues associated with it

  • In 2015Gerresheimer and Corning Inc. signed a joint venture in order to accelerate the innovations for pharmaceutical glass packaging materials. The companies entered into a 10 year supply agreement for borosilicate glass tubes focusing on packaging of pharmaceutical products.
  • In 2016, BESPAK launched SYRINA AR 2.25 auto injector that enables fully-automatic delivery of viscous drug formulations. The innovative auto-injector is specifically tailored to inject higher viscosities enabling safe use of glass syringes.

Prefilled syringes are ready to use pharmaceutical products used to deliver parenteral medications. These are mainly used for treatment of chronic conditions that require long-term and self-administration of medication. Prefilled syringes are the ideal choice for single-dose drugs, offering easy-to-use fixed dosage options, thereby helping pharmaceutical companies control costs by minimizing drug overfill, minimize microbial contamination and reduce dosing errors. Prefilled syringes make injections easier and safer for both doctors and patients, with the patient always receives the right amount of dosage without complications.

The prefilled syringes market is expected to gain steady traction in the foreseeable future, with the success and growth of biologics, increased global vaccination, increased drug self-administration trend, technological advancements in the manufacture of PFS, and development of advanced PFS would further augment market growth. For instance, Safelia auto injector developed by Nemera in 2017 won the ‘Patient Centricity & Customization’ innovation award at Pharmapack. Safelia is an innovative auto injector for prefilled syringes, available in variable sizes, suitable for large volume and high viscosity delivery through thinner needles.

Market Dynamics

Minimum environment exposure, easy administration, better patient compliance and 100% bioavailability are the factors expected to drive the prefilled syringes market growth in the forecast period. According to the World Journal of Pharmacy and Pharmaceutical Sciences 2016, more than 3.5 billion prefilled syringes are produced and used annually by patients and healthcare providers for the treatment of broad spectrum of conditions. The technological innovations and developments of prefilled syringes are contributing to the market growth. For instance, Gerresheimer introduced metal-free Luer Lock Gx RTF Syringe in 2017, without tungsten to create perfect primary packaging material for the biotechnologically manufactured active ingredients that ideally exclude the possibility of contamination with metal. However, availability of alternative systems such as nanopatches, microneedles, connected delivery devices, limited shelf life and stability issues of the drugs are the factors restraining the market growth.

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