DelveInsight has added a new research study on Urea Cycle Disorders Market Report with detailed information on the overview, market insights, drugs industry, treatment, growth, size, share, trends, during the forecast period of 2017 to 2030
Urea Cycle Disorders Overview
A Urea Cycle Disorder (UCD) is a genetic disorder that results in a deficiency of some major enzymes in the urea cycle. These enzymes are responsible for removing ammonia from the bloodstream. The urea cycle involves a series of biochemical steps in which nitrogen, a waste product of protein metabolism, is changed to a compound called urea and removed from the blood. Normally, the urea is removed from the body through the urine.
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Urea Cycle Disorders Regions Covered
- The United States
- EU5 (Germany, France, Italy, Spain, and the United Kingdom)
List of Companies in the Urea Cycle Disorders Market Report are-
- Horizon Therapeutics
- Acer Therapeutics
- Aeglea BioTherapeutics
- Kaleido Biosciences
- And many others
Urea Cycle Disorders Symptoms
The symptoms will develop within the first 24 hours of life. Symptoms in children with mild or moderate UCD, who do not show symptoms until early childhood, may include: Vomiting, nausea, mental confusion or hyperactive behavior, Tired often and / or hard to awaken, Coma, etc.
Urea Cycle Disorders Treatment
Treatment is a lifelong process that doesn’t cure the condition, but it can effectively manage the symptoms. The child’s treatment probably will involve:
- Low protein, high-calorie diet
- Amino acid supplements
- Liver transplantation
Urea Cycle Disorders Market Insights
Recent advances in the treatment of inborn errors of urea synthesis have significantly decreased mortality. The treatment of urea cycle disorders consists of dietary management to limit ammonia production, in conjunction with medications and/or supplements that provide alternative pathways for the removal of ammonia from the bloodstream.
Urea Cycle Disorders Treatment Market
Treatment involves compounds that increase the removal of nitrogen waste. These compounds convert nitrogen into products other than urea, which are then excreted; hence, the load on the urea cycle is reduced. The first compounds to be used were sodium benzoate and arginine. Later, phenylacetate was used, which has now been replaced by phenylbutyrate.
There are a number of treatments that can be effective in urea cycle disorders, but still, there are many unmet needs. Alternative pathway therapy has limited effectiveness in preventing hyperammonemia and it needs to be combined with effective dietary management. Therefore, in children with a neonatal-onset disease or in those with very poor metabolic control, liver transplantation is also considered.
Read Detailed TOC of the UCD Market Report
1. Key Insights
2. Executive Summary of Urea Cycle Disorders
3. Competitive Intelligence Analysis for Urea Cycle Disorders
4. Urea Cycle Disorders: Market Overview at a Glance
5. Urea Cycle Disorders: Disease Background and Overview
6. Patient Journey
7. Urea Cycle Disorders Epidemiology and Patient Population
8. Treatment Algorithm, Current Treatment, and Medical Practices
9. Unmet Needs
10. Key Endpoints of Urea Cycle Disorders Treatment
11. Marketed Products
12. Emerging Therapies
13. Urea Cycle Disorders: Seven Major Market Analysis
14. Attribute analysis
15. 7MM: Market Outlook
16. Access and Reimbursement Overview of Urea Cycle Disorders
17. KOL Views
18. Market Drivers
19. Market Barriers
21. DelveInsight Capabilities
23. About DelveInsight
Key Questions Answered in Urea Cycle Disorders Market Report:
- What was the Urea Cycle Disorders market share (%) distribution in 2017 and how it would look like in 2030?
- What would be the Urea Cycle Disorders total market size as well as market size by therapies across the 7MM during the forecast period (2017-2030)?
- What are the key findings pertaining to the market across 7MM and which country will have the largest Urea Cycle Disorders market size during the forecast period (2017-2030)?
- At what CAGR, the Urea Cycle Disorders market is expected to grow by 7MM during the forecast period (2017-2030)?
- What would be the Urea Cycle Disorders market outlook across the 7MM during the forecast period (2017-2030)?
- What would be the Urea Cycle Disorders market growth till 2030, and what will be the resultant market Size in the year 2030?
- How would the market drivers, barriers, and future opportunities affect the market dynamics and subsequent analysis of the associated trends?
How Does This Urea Cycle Disorders Market Insights Help?
- The report will help in developing business strategies by understanding trends shaping and driving the Urea Cycle Disorders market
- To understand the future market competition in the Urea Cycle Disorders market and Insightful review of the key market drivers and barriers
- Organize sales and marketing efforts by identifying the best opportunities for Urea Cycle Disorders in the US, Europe (Germany, Spain, Italy, France, and the United Kingdom), and Japan
- Identification of strong upcoming players in the market will help in devising strategies that will help in getting ahead of competitors
- Organize sales and marketing efforts by identifying the best opportunities for the Urea Cycle Disorders market
- To understand the future market competition in the Urea Cycle Disorders market
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