Triple Negative Breast Cancer (TNBC) Pipeline Analysis (2023) Covering Clinical Trials, Emerging Therapies, FDA, EMA, and PMDA Approvals, Competitive Landscape | Merck, Roche, Tesaro, Clovis, Gilead

Triple Negative Breast Cancer (TNBC) Pipeline Analysis (2023) Covering Clinical Trials, Emerging Therapies, FDA, EMA, and PMDA Approvals, Competitive Landscape | Merck, Roche, Tesaro, Clovis, Gilead
Delveinsight Business Research LLP
As per DelveInsight’s assessment, globally, about 75+ key pharma and biotech companies are working on 80+ pipeline drugs in the Triple Negative Breast Cancer therapeutics landscape based on different Routes of Administration (ROA), Mechanism of Action (MOA), and molecule types. Several of the therapies are in the advanced stages of clinical development and are expected to launch in the coming years.

Triple Negative Breast Cancer (TNBC) Pipeline Insight, 2023” report by DelveInsight outlines a comprehensive assessment of the present clinical/non-clinical development activities and growth prospects across the Triple Negative Breast Cancer Market. 

The Triple Negative Breast Cancer Pipeline report embraces in-depth commercial, regulatory, and Triple Negative Breast Cancer clinical trial assessment of the pipeline products from the pre-clinical developmental phase to the marketed phase. The report also covers a detailed description of the emerging Triple Negative Breast Cancer drugs, including the mechanism of action, clinical studies, NDA approvals (if any), and product development activities comprising the technology, collaborations, mergers, acquisition, funding, designations, and other product-related details.

Triple Negative Breast Cancer (TNBC) Pipeline Analysis

The report provides insights into: 

  • The report provides detailed insights into the emerging therapies for Triple Negative Breast Cancer treatment and the aggregate therapies developed by major pharma companies.

  • It accesses the different Triple Negative Breast Cancer therapies segmented into early-stage, mid-stage, and late-stage of clinical development.

  • It outlines the major Triple Negative Breast Cancer companies involved in targeted therapeutics development, with respective active and inactive (dormant or discontinued) projects.

  • The report evaluates the Triple Negative Breast Cancer drugs that are under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type. 

  • It navigates the major collaborations (company-company collaborations and company-academia collaborations), licensing agreements, financing details, data presentation by the pharma giants, and regulatory approval in the Triple Negative Breast Cancer therapeutic market.

Triple Negative Breast Cancer (TNBC) Therapeutics Landscape

Currently, the treatment paradigm for TNBC includes a few treatment options, such as systemic chemotherapies, neoadjuvant or adjuvant chemotherapy, surgery, and radiation.  The Triple Negative Breast Cancer market holds few US FDA-approved drugs, such as KEYTRUDA (pembrolizumab) by Merck Sharpe and Dohme, LYNPARZA (olaparib) by AstraZeneca, TRODELVY (sacituzumab govitecan) by Gilead Sciences, etc. However, various off-label drugs are used for treating TNBC, which include Paclitaxel (Abraxane), Erbulin (Halaven), Carboplatin, Cisplatin, Docetaxel, etc. 

TNBC is a type of breast cancer that does not express the estrogen and the progesterone receptors and the human epidermal growth factor receptor type 2 (HER2). Since there are no positive markers to reliably classify TNBC, these tumors are not yet treated with targeted therapies. Perhaps for this reason, they are the most aggressive form of breast carcinomas. The treatment paradigm for TNBC generally includes a combination of conventional therapies such as surgery, radiation, and chemotherapy.

Currently, the therapeutic market of TNBC accounts mainly for the systemic chemotherapies (either alone or in combination), such as Paclitaxel (Abraxane), Erbulin (Halaven), Carboplatin, Cisplatin, Docetaxel, etc. These chemotherapies are being used off-label, as both first-line and second-line treatment of TNBC patients, with variations in the dosing frequency and drug combinations.

There are approx. 75+ key companies developing therapies for Triple Negative Breast Cancer. Currently, Jiangsu HengRui Medicine is leading the therapeutics market with its Triple Negative Breast Cancer drug candidates in the most advanced stage of clinical development.

Triple Negative Breast Cancer (TNBC) Companies Actively Working in the Therapeutic Market Include:

  • Astellas

  • AstraZeneca

  • Clovis Oncology

  • CytoDyn

  • Gilead Science

  • HiberCell

  • Hoffmann-La Roche

  • Immunomedics

  • Imprime PGG

  • Infinity Pharmaceuticals

  • Merck

  • Roche

  • Tesaro

And Many Others

Emerging and Marketed Triple Negative Breast Cancer (TNBC) Drugs Covered in the Report Include:

  • Atezolizumab: Roche

  • Capitasertib: AstraZeneca

  • Cobimetinib: Roche

  • Enzalutamide: Pfizer/Astellas

  • HiberCell: Imprime PGG

  • Ipatasertib: Roche

  • IPI-549 (Eganelisib): Infinity Pharmaceuticals

  • KEYTRUDA (pembrolizumab): Merck & Co

  • Niraparib: Tesaro

  • Pembrolizumab: Merck

  • Rucaparib: Clovis Oncology

  • Sacituzumab Govitecan: Immunomedics

  • TRODELVY (sacituzumab govitecan-hziy): Gilead Sciences

  • HiberCell: Imprime PGG

  • MDNA11: Medicenna Therapeutics

  • Leronlimab (PRO 140): CytoDyn

And Many More

Request the Sample PDF to Get a Better Understanding of the Emerging Drugs and Triple Negative Breast Cancer Companies Working in the Market @

https://www.delveinsight.com/sample-request/triple-negative-breast-cancer-tnbc-pipeline-insight

Analysis of Emerging Triple Negative Breast Cancer Therapies by Phases

The report covers the emerging products under different phases of clinical development like –

  • Late-stage products (Phase III)

  • Mid-stage products (Phase II)

  • Early-stage product (Phase I) 

  • Pre-clinical and Discovery stage candidates

  • Discontinued and inactive candidates

Route of Administration

Triple Negative Breast Cancer pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as

  • Oral

  • Parenteral

  • intravenous

  • Subcutaneous

  • Topical

Molecule Type

Products have been categorized under various Molecule types such as

  • Monoclonal Antibody

  • Peptides

  • Polymer

  • Small molecule

  • Gene therapy

Learn How the Triple Negative Breast Cancer Treatment Outlook will Evolve with the Ongoing Clinical and commercial Activities in the Therapeutic Market @

https://www.delveinsight.com/sample-request/triple-negative-breast-cancer-tnbc-pipeline-insight

Table of Content (TOC)

1. Report Introduction

2. Executive Summary

3. Triple Negative Breast Cancer Treatment Patterns

4. Triple Negative Breast Cancer – DelveInsight’s Analytical Perspective

5. Therapeutic Assessment

6. Triple Negative Breast Cancer Late Stage Products (Phase-III)

7. Triple Negative Breast Cancer Mid-Stage Products (Phase-II)

8. Triple Negative Breast Cancer Early Stage Products (Phase-I)

9. Pre-clinical Products and Discovery Stage Products

10. Inactive Products

11. Dormant Products

12. Triple Negative Breast Cancer Discontinued Products

13. Triple Negative Breast Cancer Product Profiles

14. Major Triple Negative Breast Cancer Companies in the Market

15. Key Products in the Triple Negative Breast Cancer Therapeutics Segment

16. Dormant and Discontinued Products

17. Triple Negative Breast Cancer Unmet Needs

18. Triple Negative Breast Cancer Future Perspectives

19. Triple Negative Breast Cancer Analyst Review  

20. Appendix

21. Report Methodology

*The Table of Contents (TOC) is not exhaustive; the final content may vary. Refer to the sample report for the complete table of contents.

Download Sample PDF to Explore the Key Offerings of the Report @

https://www.delveinsight.com/sample-request/triple-negative-breast-cancer-tnbc-pipeline-insight

 

 

About DelveInsight

DelveInsight is a leading Business Consultant and Market Research Firm focused exclusively on life sciences. It supports pharma companies by providing comprehensive end-to-end solutions to improve their performance.

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