Sugar Based Excipients are the vital part of drug delivery in the body. Usually, an excipient has no therapeutic properties. Its purpose is to line up the manufacturing of drug product and eventually facilitate physiological absorption of the drug. The main purpose to use excipients is to facilitate absorption of the drugs by a patient, provide substance to the formulation, to provide stability and prevention from denaturation and other pharmacokinetic consideration. The Excipients might support in disintegration, taste, flowability, lubricity and some form of the antimicrobial function. In drug manufacturing process, selecting an appropriate excipient is an important step to support the design of pharmaceutical formulation.
It is mostly used in sorbitol, saccharin sodium, glycerol, and sucrose among others. Sugar based excipients are usually used in oral medication, mainly in antibiotics drugs and cough syrup for the children. Sugar based excipient lowers bitterness of the active agents. Mannitol is an expensive diluent form of the excipient among, all another kinds of sugar-based excipient, used as a chewable tablet for refreshment.
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The major factors that drive the market are the increasing enhancements of the Orally Disintegrating Tablets (ODT), rising improvement of generic drugs and increase in the usage of the co-processed excipient. The use of mannitol, in a wide range of dosage form, is growing the sugar alcohol segment among other segments in the market. The granular form of sugar-based excipient is widely used among other sugar-based excipients in the pharmaceutical industry. Some concerns have been raised against the purity, certain research center claims that impurities were found, which poses risk to patients. This may be dangerous for patients’ immune system which hampers the growth of the sugar-based excipients market. However, factors that restrain the market are the shortage of FDA approval due to the rigorous regulatory requirements.
According to the American Pharmaceutical Review, around 35 products have been launched by using Zydis ODT technology in 60 countries worldwide in 2016. Sugar alcohol differs in sweetness level and calorie content. Sweetness level of this sugar-based excipient range from 50-100% to that of sugar. According to the Food and Drug Administration (FDA), Indian firms have received 40% of new U.S. approvals for the generic drugs in the recent years.
Based on the regional analysis, the global market is segmented into North America, Europe, Asia-Pacific, and LAMEA. Due to investment in the production and drug development of the generic drugs, as well various government policies, Western and Eastern Europe is expected to command a significant market share of the global market.
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Major players in the market are Ashland Inc., Dfe Pharma, FMC Corporation, Cargill Inc., Archer Daniels Midland Company, Roquette Group, The Lubrizol Corporation, Roquette Group, Meggle AG, Associated British Foods Plc, Basf SE and Colorcon Inc. among others.
This report provides analysis of the sugar based excipients market that contains current industry trends, market size, market growth and demands, major players with their key strategies. It covers growth opportunities and market canvas in the coming years. The report has been made with an in-depth analysis along with inputs from the various industry experts. The research has being carried out with primary and secondary data sources and either supporting bottom up or top down approach.
Global Composite Testing Market Segmentation:
• Artificial Sweeteners
• Sugar Alcohols
• Actual Sugars
• Direct Compression Sugars
• Tonicity Agents
• Flavoring Agents
• Fillers & diluents
• Topical Formulations
• Parenteral Formulations
• Oral Formulations
• North America (U.S and Canada and rest of North America)
• Europe (Germany, France, Italy and Rest of Europe)
• Asia-Pacific (China, Japan, India, South Korea and Rest of Asia-Pacific)
• LAMEA (Brazil, Turkey, Saudi Arabia, South Africa and Rest of LAMEA)
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