Spinocerebellar Ataxias Treatment Market and Market Insights

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Spinocerebellar Ataxias Treatment Market and Market Insights

“Spinocerebellar Ataxias Market” report has been added to DelveInsight

 

DelveInsight’s “Spinocerebellar Ataxias Market Insights, Epidemiology, and Market Forecast-2030″ report delivers an in-depth understanding of the Spinocerebellar Ataxias , historical and forecasted epidemiology as well as the Spinocerebellar Ataxias market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan.

 

Spinocerebellar Ataxias Overview

Spinocerebellar Ataxia (SCA) is a genetic disorder which is progressive, degenerative, and often fatal. The clinical marker of all SCAs is a progressive loss of balance and coordination accompanied by slurred speech. The mobility and communicative skills of individuals with an SCA are restricted, which strongly impairs quality of life, and many SCAs lead to premature death.

 

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Spinocerebellar Ataxias Market: Regions Covered

  • The United States
  • EU5 (Germany, France, Italy, Spain, and the United Kingdom)
  • Japan

 

Spinocerebellar Ataxias Key Players

  • Biohaven Pharmaceuticals
  • Kissei Pharmaceutical
  • IntraBio
  • Steminent Biotherapeutics
  • And many others

 

Spinocerebellar Ataxias Drugs

  • Troriluzole
  • Rovatirelin (KPS-0373)
  • IB1001
  • Stemchymal
  • And many others

 

Spinocerebellar Ataxias Treatment

Current treatment pipelines involve the use of pharmacological molecules to target affected downstream pathways, as well as genetic therapies to decrease toxic polyQ gene products. The path to effective therapies for SCAs is hampered by their heterogeneity; specific therapeutic approaches may be required for each genotype.

 

Spinocerebellar Ataxias Market Report

Genetically, the SCAs fall into two major groups: those caused by dynamic repeat expansion mutations (repeat expansion SCAs) and those caused by nonrepeating mutations. Further, repeat expansions are also a major cause of non-SCA inherited neurological diseases. There are at least 12 repeat expansion SCAs. Six of these diseases—SCA1, SCA2, SCA3/Machado–Joseph disease, SCA6, SCA7, and SCA17 are caused by translated CAG repeat expansion mutations that encode stretches of pure glutamine in the respective disease proteins; these diseases are thus referred to as polyglutamine SCAs.

 

Spinocerebellar Ataxias Treatment Market

Spinocerebellar Ataxia (SCA) treatment landscape is currently devoid of any approved therapies. The clinical care of patients with SCA focuses on managing the symptoms through physiotherapy, occupational therapy, and speech therapy. Intense research has greatly expanded understanding of the pathobiology of many SCAs, revealing that they occur via interrelated mechanisms (including proteotoxicity, RNA toxicity, and ion channel dysfunction), and has led to the identification of new targets for treatment development.

 

Spinocerebellar Ataxias Market Insights

However, the diagnosis, prognosis, and management of spinocerebellar ataxia (SCA) continue to be challenging in current practice. This is related to an incomplete understanding of the pathophysiology of the disease process, complexity of initiating factors, and a lack of evidence-based standardized therapies. Various genes have been identified in which mutations can lead to SCA.

 

Spinocerebellar Ataxias Expected Emerging Therapies

  • Troriluzole (BHV-4157) (Biohaven Pharmaceuticals)
  • KPS-0373 (Rovatirelin) (Kissei Pharmaceuticals) 

 

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Table of content

1. Key Insights

2. Executive Summary of Spinocerebellar Ataxias

3. Competitive Intelligence Analysis for Spinocerebellar Ataxias

4. Spinocerebellar Ataxias: Market Overview at a Glance

5. Spinocerebellar Ataxias: Disease Background and Overview

6. Patient Journey

7. Spinocerebellar Ataxias Epidemiology and Patient Population

8. Treatment Algorithm, Current Treatment, and Medical Practices

9. Unmet Needs

10. Key Endpoints of Spinocerebellar Ataxias Treatment

11. Marketed Products

12. Emerging Therapies

13. Spinocerebellar Ataxias: Seven Major Market Analysis

14. Attribute analysis

15. 7MM: Market Outlook

16. Access and Reimbursement Overview of Spinocerebellar Ataxias

17. KOL Views

18. Market Drivers

19. Market Barriers

20. Appendix

21. DelveInsight Capabilities

22. Disclaimer

23. About DelveInsight

 

Spinocerebellar Ataxias Market Drivers

  • Increasing R&D Activities
  • Market Share Potential
  • Entry of the Emerging novel therapeutic approaches
  • Rising Awareness

 

Spinocerebellar Ataxias Market Barriers

  • Lack of Clinically Relevant Biomarker
  • Lack of sensitive and unbiased measures to anticipate disease progression
  • Lack of therapies for all SCA forms
  • Disease Complex Pathophysiology

 

Spinocerebellar Ataxias Research Methodology

The objective of updating DelveInsight coverage is to ensure that it represents the most up-to-date vision of the industry possible. The DelveInsight is a fully integrated solution for comprehensive intelligence on various pharmaceutical products, both in the market and in the pipeline, across the globe.

 

 

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