(Albany,US) DelveInsight has launched a new report on “Small Fiber Neuropathy (SFN) – Market Insights, Epidemiology, and Market Forecast-2030″.
DelveInsight’s “Small Fiber Neuropathy (SFN) – Market Insights, Epidemiology, and Market Forecast-2030“ report delivers an in-depth understanding of the Small Fiber Neuropathy (SFN) , historical and forecasted epidemiology as well as the Small Fiber Neuropathy (SFN) market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan.
Some of the Key Facts:
- The Netherlands survey found overall minimum prevalence was 52.95 cases per 100,000.
- United States has the highest percentage of prevalent diagnosed & treated patients,
- The lowest prevalent population of SFN was recorded in Japan.
- Among the SFN patients, Older Adults show higher proportion of SFN as compared to adults in the 7MM.
Scope of the Report:
- The report covers the descriptive overview of Small Fiber Neuropathy (SFN) , explaining its causes, signs and symptoms, pathophysiology, diagnosis and currently available therapies
- Comprehensive insight has been provided into the Small Fiber Neuropathy (SFN) epidemiology and treatment in the 7MM
- Additionally, an all-inclusive account of both the current and emerging therapies for Small Fiber Neuropathy (SFN) are provided, along with the assessment of new therapies, which will have an impact on the current treatment landscape
- A detailed review of Small Fiber Neuropathy (SFN) market; historical and forecasted is included in the report, covering drug outreach in the 7MM
- The report provides an edge while developing business strategies, by understanding trends shaping and driving the global Small Fiber Neuropathy (SFN) market
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According to DelveInsight’s analysis, SFN is most common in males than females.
Small Fiber Neuropathy (SFN) is a condition that generally affects the nervous system and is marked by severe pain attacks. It occurs when damage to the peripheral nerves predominantly or entirely affects the small myelinated (Aδ) fibers unmyelinated C fibers thus called as Small Fiber Peripheral Neuropathy. It generally affects the small nerve fibers present in the skin and those responsible to mediate pain and thermal sensation. The specific fiber types involved in this process include both small somatic and autonomic fibers.
Most small fiber neuropathies occur in a length-dependent fashion, resulting in loss of function in a stocking distribution in the lower extremities. When the condition is more advanced, a glove-like loss in the upper extremities also may occur. In rare cases, a non–length dependent neuropathy results in symptoms involving the trunk, face, proximal limbs, or other focal areas.
SFN is caused by mutations in the SCN9A or SCN10A gene. Both the gene instructs the production of the alpha subunit for the NaV1.7 sodium channel. The SCN9A gene mutations result in NaV1.7 sodium channels that do not close completely when the channel is turned off and many SCN10A gene mutations results in opening of NaV1.8 sodium channels that more easily than usual. This increase in sodium ions enhances transmission of pain signals, causing individuals to be more sensitive to stimulation.
SFN is mainly associated with autoimmune diseases, sodium channel gene variants, diabetes mellitus, and vitamin B12 deficiencies, although in more than one-half of patients no etiology can be identified. Based on these etiologies, it can be divided in to four sub-groups such as Acquired SFN, Hereditary SFN, Syndromic SFN, and Idiopathic SFN.
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The symptoms of SFN include bowel problems, urinary issues, rapid heartbeat, abnormal sweating, and dry eyes and mouth. It is generally characterized by severe pain attacks that begin in the feet or hands.
Some of the Companies Covered:
- Vertex Pharmaceuticals Incorporated
- Biogen
- Takeda
- And Many Others
Drugs Covered:
- VX-150
- BIIB074
- Gammagard IVIG
- And Many Others
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Table of Contents:
1. Key Insights
2. Executive Summary of Small Fiber Neuropathy (SFN)
3. Competitive Intelligence Analysis for Small Fiber Neuropathy (SFN)
4. Small Fiber Neuropathy (SFN) : Market Overview at a Glance
5. Small Fiber Neuropathy (SFN) : Disease Background and Overview
6. Patient Journey
7. Small Fiber Neuropathy (SFN) Epidemiology and Patient Population
8. Treatment Algorithm, Current Treatment, and Medical Practices
9. Unmet Needs
10. Key Endpoints of Small Fiber Neuropathy (SFN) Treatment
11. Marketed Products
12. Emerging Therapies
13. Small Fiber Neuropathy (SFN) : Seven Major Market Analysis
14. Attribute analysis
15. 7MM: Market Outlook
16. Access and Reimbursement Overview of Small Fiber Neuropathy (SFN)
17. KOL Views
18. Market Drivers
19. Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer
23. About DelveInsight
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Country: United States
Website: https://www.delveinsight.com/report-store/small-fiber-neuropathy-market