New York, Mar 27th, 2019 – Profacgen, a leading custom protein services in the biological sciences provider, recently launches the newest version of PEGylation Products and Services, which is widely applied to prolong circulation time of proteins, increase aqueous solubility of therapeutic molecules and reduce immunogenicity of biopharmaceuticals, accordingly making them capable to enhance stability and pharmacological properties of proteins, peptides, antibody-drug conjugates and small-molecule drugs.
Profacgen offers a range of techniques for site-specific binding of polyethylene glycol (PEG) or other polymers to therapeutic proteins and peptides. Conjugation of PEG (PEGylation) is a well-established method for prolonging the half-life and thus prolonging the duration of action of therapeutic proteins, including antibody fragments. We offer a range of PEGylation techniques for use with PEGs of different molecular weights in linear and branched form. They are designed to conjugate PEG to disulfide bonds, thiols or polyhistidine motifs on monocysteine.
At present, there are two main types of PEG reagents, including linear PEG and branched PEG, which are used in commercially available drugs. With years of experience in bioconjugation services, Profacgen offers a full range of quality solutions, ranging from single reagents to comprehensive PEGylation services to meet your specific needs.
In profacgen, we offer activated linear and branched derivatives of polyethylene glycol (PEG) for pegylation and PEG modification of peptides and proteins by primary and thiol groups. These agents are commonly used to increase solubility, extend stability and reduce immunogenicity. Certain experimental systems and assay platforms depend on the ability to alter the quality, solubility or other properties of proteins, immunogens, reaction vessels and other materials. The custom PEGylation services include a comprehensive set of services for proteins, peptides, oligonucleotides and small molecules, and custom synthesis of PEG derivatives, such as protein/peptide-PEG conjugation, and small-molecule PEGylation, as well as custom synthesis of innovative PEGylation reagents and derivatives to meets the unique requirements.
‘Except for the PEGylation Services we provided, Profacgen also offers a wide range of high purity functionalized PEG products to meet the needs of our customers.’ Said Ellen Burns, the marketing director of Profacgen, ‘Our current single-function PEG products, including amine-reactive PEG, carboxyl-reactive PEG and thiol-reactive PEG, provide efficient PEGylation of your target protein using simple but reliable chemistry.’
Located in Long Island, NY, USA, Profacgen started with protein expression and purification, producing recombinant proteins according to our customer specifications or by developing customized protocols in house. With a professional team focusing on protein interaction analysis and high-throughput screening services, Profacgen has become a well-recognized industry leader supporting scientists worldwide.
Company Name: Profacgen
Contact Person: Ellen Burns
Email: Send Email
Address:45-1 Ramsey Road
State: New York
Country: United States