Ou MC decrescendo phenomenon (OuDP) is induced by interaction between human bilateral features and has shown to alleviate or cure a variety of diseases. The resolution of dysfunctional conditions with OuDP indicates to be consistent with restoration of normal tissue function (Am J Emerg Med, 2012; Proc Physiol Soc, 2014-2016; Cancer res, 2016; Acta Physiologica, 2017; TJOG, 2017; IJGC, 2018; JARG, 2018). OuDP was induced by applying the hand to the contralateral body.

Ming Cheh Ou et al. provides the phenomenal observation through various groups studies that Ou MC Decrescendo Phenomenon (OuDP), invoked by a therapist or the patient himself with placing the contralateral hand over a diseased location to produce a zone under the hand with decreased pain or inflammation. OuDP can bring about immediate clinical effects, long-term functional improvements, or even a cure for diseases. OuDP treatment acts quite different from conventional manual therapy.

Ou MC Manipulation is a diagnostic procedure to place the contralateral hand on the pelvic ring to separate the pelvic region from another abdominal area, in which the reduction of pain under the contralateral hand can delimit the pelvic region for differentiating pelvic disease from non-pelvic diseases. It shows no significant difference between therapist- and self-induced OuDP for relieving pain.

Experimental Analysis of Ou DP

Ming Cheh Ou et al. talks about two front-end studies conducted between 2006 and 2011 for experimental analysis of Ou MC Decrescendo Phenomenon. These hands-on therapies were conducted to identify the hand-placement method (contralateral or ipsilateral) that alleviates the symptoms better. For example, the first study was conducted using a deeply placed contralateral hand in the affected location, and it was found to alleviate the acute abdominal pain of 42 women. The second study compared the effects of using either the contralateral hand or the ipsilateral hand for the therapy. It was found that the use of contralateral hand alleviated the pain of 92.3% of women (36/39), while the ipsilateral hand did not.

Group Study with Application of OuDP treatment (OuDPt)

Ming Cheh Ou et al. present studies on a series of patients with various diseases that resolved with the application of OuDPt, to conclude the effectiveness of OuDP. This group study was conducted in Taiwan between June 2011 and Nov 2013. A total of 38 patients were chosen for this research, out of which 27 were trained to self-administer OuDPt and the other 11 received OuDPt by the therapist.

Pre-conditions

• None of the patients had metabolic or immunological diseases. All patients refrained from medication during the study period, except for three patients who used antibiotics.
• The mean age of the patients (17 men, 21 women) was 55.8 years (standard deviation, 22.9 years).
• Based on the preliminary findings from the front-end studies (mentioned earlier) only the contralateral hand was used for the OuDPt in this study.

Ming Cheh Ou et al. brings out some of the practical points while applying OuDP treatment to patients. This includes placement of the hand for lesions on or adjoining the midline of the body, the effective positioning of the patients, and the factors that can reduce the effectiveness of the therapy. Some of the most effective ways of placing the contralateral hand during the therapy are explained using appropriate diagrams. The amount of pressure that needs to be applied depends on the depth of the lesion, with greater pressure being applied to deeper lesions. If the palm cannot reach the affected area, fingers can be used.

Group Analysis

The patients were divided into three groups:

1. Group 1 comprised of eleven patients with symptoms or signs related to infection treated with self-administered OuDPt.
2. Group 2 with sixteen patients having symptoms or signs not related to infection treated with self-administered OuDPt.
3. Group 3 with eleven patients treated by the therapist.

The effects of OuDP on the symptoms of the diseases related and unrelated to the infection were studied. This was for Group 1 and 2 respectively. The effects of OuDP using the therapist-administered OuDP treatment on the symptoms of the diseases related to the infections were also studied, which was on Group 3.

In Group 1, patients with recurrent oropharyngeal infections, infections in the sublingual and gingival area, infectious granuloma, cellulitis infections on the leg, rhinorrhea, and facial warts were self-administered with OuDPt. All the patients showed suppression of symptoms with OuDPt, even though the complete cure was not guaranteed in some cases.

In Group 2, patients with joint tenderness, swelling of the periorbital area, perineal macula skin lesion, supine cough, defecation difficulty with decreasing stool caliber, parkinsonism, and leiomyosarcoma were self-administered with OuDPt. All the patients showed milder or reduced symptoms after OuDPt.

In Group 3, patients with recurrent biliary tract infection, intractable pyuria, right intractable tuboovarian abscess, left hip joint pain, right knee joint pain, right lumbago, bilateral gluteal pain, acute whipping injury, and soft tissue pain were administered OuDPt by a therapist. All the patients showed alleviation of symptoms after the therapy.

Evaluation Methods

Symptoms and signs were evaluated immediately before and five minutes after application of OuDPt. A Visual Analog Scale (VAS) was used to evaluate the severity of pain in patients.To evaluate the clinical anxiety of patients during the therapy, the Generalized Anxiety Disorder-7 item scale (GAD-7) was used. During the treatment, all patients showed a GAD-7 less than 7, which meant that clinical anxiety was not present and may not have influenced the study results. The sign test and Fisher’s exact test were used as the statistical methods in this study.

Evaluation Results

The OuDP demonstrated significant immediate effects among both self-administered groups and the therapist-administered group. In the self-administered groups it was 20/20, 100%, 7 unevaluated, and in the therapist-administered group it was 10/10, 100%, 1 unevaluated.

Ming Cheh Ou et al. points out that there are some limitations in this study which include the less number of patients, less accurate evaluation of clinical anxiety, and failure to invoke OuDP in certain cases. The OuDP therapies show the extent to which the symptoms are reduced using a specific hand-placement method.

Abdominal Palpation with Ou MC Manipulation or APOM

Ming Cheh Ou et al. makes yet another study in which Ou MC Manipulation can be used for abdominal palpitation, that is used for the treatment of acute abdomen in women. Abdominal palpation is an important procedure for identifying the location of abdominal tenderness in women suffering from the acute abdomen, caused by Pelvic Inflammatory Disease (PID).

Abdominal Palpation with Ou MC Manipulation or APOM is performed by isolating the pelvic area by means of manual pressure, along with a line from the sub-umbilicus to the femoral arterial canal of the inguinal area, thus isolating the pelvic organs from other abdominal organs. In this way, APOM separates the abdominal cavity into two compartments and categorizes the abdominal pain as identified within or outside the pelvic area. This helps to identify and compare tenderness and to easily locate the diseased organ.

Thus, APOM can differentiate the pain arising from pelvic organs more effectively contrary to the other methods like a bimanual pelvic examination or routine lower abdominal palpation.

Ming Cheh Ou et al. provides an example pilot study conducted on 68 women diagnosed with Pelvic Inflammatory Disease between 2006 and 2009. In this study, APOM yielded greater sensitivity for localizing pelvic pain and located diseased pelvic organs effectively than the bimanual pelvic examination (p = 0.013, McNemar test). Through this study, Ming Cheh Ou et al. concludes that APOM has the potential for a more accurate clinical diagnosis of PID for women with an acute abdomen. However, there are certain limitations in this analysis because the study was conducted only on women finally diagnosed with PID, but it should also have been conducted on an undifferentiated population of women suffering from lower abdominal pain.

Ming Cheh Ou et al. provides yet another study where APOM can also be used in pregnant women with acute abdomen, to effectively locate tenderness, avoiding hard compression on the uterus. In this study, OuDP was induced with the contralateral hand of the examiner, by pressing the hand in a chopping gesture lightly on the abdomen, along the contour of the uterus.

OuDPt and Axes of Embryonic Polarity

Ming Cheh Ou et al. proves that the OuDP induced via the interaction between human bilateral parts results in normalization of tissue functions, and this suggests that the axes of embryonic polarity may impart the OuDP. Based on different studies, Ming Cheh Ou et al. observes that OuDPt is effective in producing the OuDP with the contralateral hand, but not the ipsilateral hand. This finding implies that the axes of embryonic polarity, especially the left-right axis, form the potential mechanism underlying the OuDP.

Preliminary study about OuDPt application on Cancer Regression

Ming Cheh Ou et al. extends the application of OuDPt in the treatment of cancer and OuDPt was found to restore the normal tissue function. In this study, four female patients underwent self-administered OuDPt separately for their cancerous diseases from 2011 to 2014, OuDPt was used to induce OuDP by applying the hand to the contralateral body. The treatments with OuDPt showed suppression or reduction of oncologic changes for these patients.

Through this study, Ming Cheh Ou et al. reveals that OuDP can normalize the tumor cells and microenvironment function, which makes the tumor cells conform to the regulations with apoptosis and metastasis suppression. This prevents uninhibited proliferation, and also minimizes angiogenesis and supervision by host immunological systems.

Tumour Regression, Suppression of Neoplasm, and Anti-inflammatory Effects of OuDP

OuDP is presumed to be caused by the interaction of human body anatomical axis (HBAA), and more of HBAAs interactions can enhance the effect. A study was conducted in 2016 on three female patients, where all patients received OuDP through 3 HBAAs—vertical, left-right, and dorsoventral axis, which formed a three-dimensional body polarity system. After the OuDPt, it was found that endometrial cancer and ovarian cancer regressed. The size of small suspected pancreatic cancer decreased and the tumor subsided after one year. From this study, Ming Cheh Ou et al. conclude that OuDP shows tumor suppression effect. Since more HBAAs interaction enhances OuDP effect, it follows that OuDP is induced by HBAA interaction.

In yet another study, Ming Cheh Ou et al. show that OuDP treatment with the 3D human body polarity system comprising left-right, dorsoventral, and vertical HBAAs suppresses the development of the neoplasm more efficiently than OuDP treatment with 2D polarity body system. The study was conducted after observing a set of eight patients with neoplastic diseases from 2011 to 2015, three of whom did not receive other anti-cancer treatment for their separate diseases. The neoplasm of these three patients was found to be improved by OuDP treatment via 2 HBAAs. All these three patients performed OuDP treatment with all 3 HBAAs, which formed a 3 dimensional (3D) polarity system.

The studies show that OuDP treatment may probably directly normalize the dysfunctional cells rather than acting indirectly through reinforcement by the neighboring normal cells. It is found that OuDP can reduce immediate effects on pain, inflammation, and uterine neoplasm bleeding, and this is too fast to be concluded as an indirect effect.

In another study, Ming Cheh Ou et al. show that OuDPt has anti-inflammatory effects on patients. From 2015 to 2018, a study was conducted on 9 patients with recurrent dysmenorrhea. All the patients received OuDPt in a 2 dimensional way, twice daily or more in the menstrual period on the painful area. The results showed that OuDP prominently alleviated the dysmenorrhea of all 9 patients without any analgesic treatment. Ming Cheh Ou et al. conclude that OuDP helped in tissue function normalization, which decreased the release of inflammatory chemicals, consequently reducing the inflammation.

Limitations of OuDPt

Ming Cheh Ou et al. observes some limitations in the studies conducted with respect to OuDPt. OuDPt appears to be consistently effective for a wide variety of diseases, However, normalization of tissue function may not always be sufficient to resolve diseases. OuDPt is effective for pain induced by a dysfunctional tissue as that of degenerative joint disease or endometriosis pain, but may not be sufficient to treat a disease beyond tissue dysfunction as that of an infection. OuDP can be produced via the interaction of the therapist and the patient. Such interactions may be interfered by unknown factors. OuDPt shows the suppressive effect on advanced cancer. Such an effect may not be well induced for lesions that cannot be fully accessed. Studies show certain cell polarity molecules may suppress the neoplasm growth but some others enhance Further evaluation of OuDP for cancer are warranted. While OuDP shows to suppress cancer growth, no cancer cell morphologic changes can be demonstrated. Thus, OuDPt may only induce cell polarity change for cancer and cancer cells may escape the suppression effect by adaption to ensure growth.

Also, The appropriate duration, frequency, method of OuDPt application for the treatment of different diseases requires further study.

On the basis of various studies, Ming Cheh Ou et al. mentions that the mechanism of action of OuDPt remains unclear, but the potential roles of several sensory factors need exploration.

Conclusion

The OuDPt is found to accelerate the recovery of infections, inflammation, degenerative diseases, organ dysfunction, and malignant oncologic changes.

The effectiveness of OuDPt can be increased by decreasing the distance between the hand and the lesion, increasing treatment duration, and increasing the treatment frequency. OuDPt helps in restoration of normal tissue function. But in some cases, restoration alone is not always sufficient to cure the disease.

Invocation of OuDP provides immediate and long-term effects on patients suffering from tissue dysfunctional conditions. Ming Cheh Ou et al. concludes that OuDPt is different from conventional or known ways and can become a new way of exploring human physiology and diseases in the near future.

About Dr. Ou Ming-Cheh

Education, Training & Workshops:

1974~1981 Taipei Medical College Undergraduate

1981~1989 Taipei Veterans General Hospital

1982~1984 Tokyo University Hospital

1989~1994 Yang Ming Medical University Clinical research institute & Taipei City Hospital

1995~2002 Taipei Chung Shan Hospital & Taipei Medical University Hospital

2002~2003 Tzu Chi Medical Center (Chief, Dept of Obs& Gyn, Tzu ChiUniversity)

2003~2005 Taichung Jen Ai Hospital (Chief of Infertility department)

2005 ~ Now Taipei City Hospital (Chief, Dept of Obs& Gyn, Zhong-Xiao branch of Taipei City Hospital)

Academic:

1995 ~ Now Associate Professor of Taipei Medical University

Honor:

2000 ~ 52th International Session of Japan Society of Obstetrics and Gynecology Academic Prize

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