Creative Diagnostics, a global leader in the development of life science research reagents, is continuing to expand its offering of ELISA products with the launch of the Human Zonulin ELISA Kit (Cat.No: DEIA6690). This newly released enzyme immuno assay can be used for the quantitative determination of Zonulin in serum, EDTA-plasma or stool.
Zonulin is a novel human protein analogue to the Vibrio cholerae derived Zonula ccludens toxin, which participates in tight junctions between cells of the wall of the digestive tract. Zonulin binds to a specific receptor on the surface of intestinal epithelia and triggers a cascade of biochemical events which induces tight junction disassembly and a subsequent permeability increase of the intestinal epithelia, allowing some substances to pass through and activate immune reactions.
“This assay is based on the method of competitive enzyme linked immunoassays. As a first preparation step, a biotinylated zonulin tracer is added to the samples, standards and controls. Afterwards, aliquots of the treated preparations are transferred and incubated in microtiter plate wells coated with polyclonal anti zonulin antibodies…” explained Dr. Jessica Waldorf, chief scientific officer of R&D department of Creative Diagnostics.
“With a strong dedication to quality and customer service since its foundation, Creative Diagnostics always supports its clients especially in the fields of bioassays, microbiology, in vitro toxicology, pharmacology, and biocompatibility, etc. For those pharmaceutical and biotech companies worldwide, Creative Diagnostics is always your trusted and experienced immunoassay expert and partner,” said Dr. Randy S. Vaughn, senior researcher at Creative Diagnostics.
For more detailed information about the zonulin ELISA, please contact Creative Diagnostics at 1-631-619-7922 or email to contact@creative-diagnostics.com
About Creative Diagnostics
Creative Diagnostics is a leading manufacturer and supplier of antibodies, viral antigens, innovative diagnostic components and critical assay reagents. It also provides contract biologic R&D and manufacturing services to the diagnostic manufacturers along with GMP biologics manufacturing for the biopharmaceutical market. It aims to provide a trusted source for all researchers’ assay development and manufacturing needs.
Media Contact
Company Name: Creative Diagnostics
Contact Person: Thomas Schmitt
Email: contact@creative-diagnostics.com
Phone: 1-631-619-7922
Address:45-1 Ramsey Road
City: Shirley
State: NY
Country: United States
Website: http://www.creative-diagnostics.com/