Key players such as Takeda, Omeros Corporation and others are developing therapies to enhance treatment modalities in the Thrombotic Thrombocytopenic Purpura market

Key players such as Takeda, Omeros Corporation and others are developing therapies to enhance treatment modalities in the Thrombotic Thrombocytopenic Purpura market
Thrombotic Thrombocytopenic Purpura Market
The Thrombotic Thrombocytopenic Purpura market size is anticipated to grow due to pharmaceutical companies’ extensive research and development activities and upcoming therapies

DelveInsight’s Thrombotic Thrombocytopenic Purpura market report thoroughly explains the Thrombotic Thrombocytopenic Purpura historical and forecasted epidemiology and the Thrombotic Thrombocytopenic Purpura market trends in the 7MM. 

Key Takeaways from the Thrombotic Thrombocytopenic Purpura Market Report 

  • According to Borborema et al. (2020), the Oklahoma TTP-HUS registry, representing a population base of 2 million individuals has found a family with cTTP every 26 years.

  • According to Chiasakul and Cuker (2018), iTTP is extremely rare – it is estimated that only 5% of all cases of TTP are inherited. In contrast, aTTP accounts for approximately 95% of all cases of TTP.

  • The leading companies in the Thrombotic Thrombocytopenic Purpura market include Takeda, Omeros Corporation, and others.

  • Key Thrombotic Thrombocytopenic Purpura therapies in the pipeline include TAK-755 (BAX930/SHP655), Narsoplimab (OMS721), and others.

  • Takeda’s TAK-755 (BAX930/SHP655) is a human recombinant ADAMTS13, a plasma metalloprotease that regulates von Willebrand Factor (VWF) multimers. The drug is intended to be an alternative to the current ADAMTS13 replacement, which uses large volumes of fresh frozen plasma containing variable amounts of ADAMTS13 and typically takes two hours or more to prepare and infuse.

  • Narsoplimab (OMS721) by Omeros Corporation is an intravenous human monoclonal antibody that targets mannan-binding lectin-associated serine protease-2 (MASP-2), an effector enzyme of the complement system’s lectin pathway.

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Thrombotic Thrombocytopenic Purpura: Overview

Thrombotic Thrombocytopenic Purpura (TTP), first identified by Singer in 1947, is a rare and life-threatening thrombotic microangiopathy characterised by microangiopathic hemolytic anaemia, severe thrombocytopenia, and organ ischemia linked to disseminated microvascular platelet rich-thrombi.

Thrombotic Thrombocytopenic Purpura Epidemiology Segmentation

The Thrombotic Thrombocytopenic Purpura report proffers epidemiological analysis for the study period 2018-30 in the 7MM segmented into:

  • Thrombotic Thrombocytopenic Purpura Total Diagnosed Prevalent Cases

  • Thrombotic Thrombocytopenic Purpura Type Specific Prevalent Cases 

  • Acquired Thrombotic Thrombocytopenic Purpura Age-Specific Diagnosed Prevalent Cases

  • Acquired Thrombotic Thrombocytopenic Purpura Gender-Specific Diagnosed Prevalent Cases

  • Congenital Thrombotic Thrombocytopenic Purpura Age-Specific Diagnosed Prevalent Cases

  • Congenital Thrombotic Thrombocytopenic Purpura Gender-Specific Diagnosed Prevalent Cases

Thrombotic Thrombocytopenic Purpura Treatment Landscape

The current TTP treatment options include Plasma therapy, immunosuppressive therapy, and Glucocorticosteroids. Some FDA-approved drugs such as Rituximab, Octaplas, and others are also used in the TTP treatment. 

Thrombotic Thrombocytopenic Purpura Market Outlook

The Thrombotic Thrombocytopenic Purpura market size is anticipated to grow due to pharmaceutical companies’ extensive research and development activities and upcoming therapies such as TAK-755 (BAX930/SHP655), Narsoplimab (OMS721), and others during the forecast period (2021-30).

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Thrombotic Thrombocytopenic Purpura Pipeline Therapies and Key Companies 

  • TAK-755 (BAX930/SHP655): Takeda

  • Narsoplimab (OMS721): Omeros Corporation

Table of Contents

1.

Key Insights

2.

Report Introduction

3.

Thrombotic Thrombocytopenic Purpura (TTP) Market Overview at a Glance

4.

Thrombotic Thrombocytopenic Purpura Market: Future Perspective

5.

Executive Summary of Thrombotic Thrombocytopenic Purpura (TTP)

6.

Key Events

7.

TTP Disease Background and Overview

8.

TTP Treatment and Management

9.

TTP Epidemiology and Patient Population

10.

TTP Patient Journey

11.

TTP Marketed Drugs

12.

TTP Emerging Drugs

13.

Thrombotic Thrombocytopenic Purpura (TTP): 7MM Market Analysis

14.

7MM Thrombotic Thrombocytopenic Purpura (TTP): Country-Wise Market Analysis

15.

KOL Views

16.

TTP Market Drivers

17.

TTP Market Barriers

18.

SWOT Analysis

19.

TTP Unmet Needs

20.

TTP Reimbursement and Market Access

21.

Appendix

22.

DelveInsight Capabilities

23.

Disclaimer

24.

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