DelveInsight’s “Hodgkin’s Lymphoma Market Insights, Epidemiology, and Market Forecast 2032” report delivers an in-depth understanding of the disease, historical and forecasted epidemiology, as well as the Hodgkin’s Lymphoma market size, share, trends, and growth opportunities in the seven major markets (7MM) (i.e., the United States, EU4 (Germany, Spain, Italy, France), the United Kingdom and Japan).
The report covers emerging Hodgkin’s Lymphoma drugs, current treatment practices, market share of individual therapies, and current & forecasted market size from 2019 to 2032. It also evaluates the current Hodgkin’s Lymphoma treatment practice/algorithm, key drivers & barriers impacting the market growth, and unmet medical needs to curate the best of the opportunities and assess the underlying potential of the market.
Hodgkin’s Lymphoma: An Overview
According to the National Organization for Rare Diseases, Hodgkin’s disease comprises a group of cancers, which are known as lymphoma. Lymphoma is a general term used to describe cancers that affect the lymphatic system, especially the lymph nodes. Tumors often form in the lymph nodes and/or the area around the nodes.
With the help of some preliminary research, it has been seen that Hodgkin lymphoma can result due to multifactorial causes. These are due to an infectious agent, such as a virus (e.g., Epstein Barr Virus). Recent studies indicate that there may be a genetic susceptibility to Hodgkin’s disease in the young adult form of the disorder as well, environmental factors or immune system deficiencies may also play a role in the development of Hodgkin’s disease. Usually, the first sign of Hodgkin’s disease is a swollen lymph node. Two-thirds of the time, a lymph node in the neck is affected. Otherwise, lymph nodes in the armpits, chest, groin, or abdomen are affected. The disease may also spread to other lymph nodes, the area around the nodes, the spleen, liver, lungs, and bone marrow.
A variety of X-ray tests may be used to determine how far the disease has spread including CT scans, magnetic resonance imaging (MRIs), and a special x-ray technique that focuses on the lymphatic system (lymphangiogram). Treatment of Hodgkin’s disease depends on the stage of the disease. Radiotherapy and/or chemotherapy are the two main treatment options.
Hodgkin’s Lymphoma Market Key Facts
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According to the National Organization of Rare Diseases (NORD), the majority of individuals with the adult form of Hodgkin’s disease are between 15 and 40 years of age at the time of diagnosis. A smaller number of individuals are affected after the age of 50. Hodgkin’s disease may also affect children. HL disease accounts for less than 1% of all cases of cancer in the United States.
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As per a systemic review by Hjalgrim et al., (2013) titled, “Epidemiology of Hodgkin Lymphoma”, Hodgkin lymphoma is a lymphatic malignancy with an estimated annual incidence of 80,000 cases worldwide.
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As per the NHS (UK), Hodgkin lymphoma can develop at any age, but it mostly affects young adults in their early 20s and older adults over the age of 70. Slightly more men than women are affected. Around 2,100 people are diagnosed with Hodgkin lymphoma in the UK each year.
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The American Cancer Society’s estimates for Hodgkin lymphoma in the United States for 2021 are about 8,830 new cases (4,830 in males and 4,000 in females). Moreover, it was reported that both children and adults can develop Hodgkin lymphoma, but it’s most common in early adulthood (especially in a person’s 20s).
The market outlook section of the report helps to build a detailed comprehension of the historical, current, and forecasted market size by analyzing the impact of current and emerging Hodgkin’s Lymphoma pipeline therapies. It also thoroughly assesses the Hodgkin’s Lymphoma market drivers & barriers, unmet needs, and emerging technologies set to impact the market dynamics.
The report gives complete details of the market trend for each marketed Hodgkin’s Lymphoma drug and mid & late-stage pipeline therapies by evaluating their impact based on the annual cost of therapy, their Mechanism of Action (MOA), Route of Administration (ROA), molecule types, competition with other therapies, brand value, and their impact on the market.
Hodgkin’s Lymphoma Epidemiology Assessment
The epidemiology section provides insights into the historical, current, and forecasted Hodgkin’s Lymphoma epidemiology trends in the seven major countries (7MM) from 2019 to 2032. It helps to recognize the causes of current and forecasted Hodgkin’s Lymphoma epidemiology trends by exploring numerous studies and research. The epidemiology section also provides a detailed analysis of diagnosed and prevalent patient pools, future trends, and views of key opinion leaders.
The Report Covers the Hodgkin’s Lymphoma Epidemiology, Segmented as –
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Total Incident Cases of Hodgkin’s Lymphoma
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Age-specific incident Cases of Hodgkin’s Lymphoma
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Gender-specific incident Cases of Hodgkin’s Lymphoma
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Incident Population of Relapsed/ Refractory form of Hodgkin Lymphoma
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Treatable cases of Relapsed/ Refractory Hodgkin Lymphoma (R/R HL)]
Hodgkin’s Lymphoma Drugs Uptake and Pipeline Development Activities
The drug uptake section focuses on the uptake rate of potential drugs recently launched in the Hodgkin’s Lymphoma market or expected to be launched during the study period. The analysis covers the Hodgkin’s Lymphoma market uptake by drugs, patient uptake by therapies, and sales of each drug. Moreover, the therapeutics assessment section helps understand the market dynamics by drug sales, the most rapid drug uptake, and the reasons behind the maximal use of particular drugs. Additionally, it compares the Hodgkin’s Lymphoma drugs based on their sale and market share.
The report also covers the Hodgkin’s Lymphoma pipeline development activities. It provides valuable insights about different therapeutic candidates in various stages and the key Hodgkin’s Lymphoma companies involved in developing targeted therapeutics. It also analyzes recent developments such as collaborations, acquisitions, mergers, licensing patent details, and other information for emerging therapies.
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Hodgkin’s Lymphoma Therapeutics Analysis
Chemotherapy and radiation therapy are the main treatments for Hodgkin Lymphoma. Depending on the case, one or both of these treatments might be used. Certain patients might be treated with immunotherapy or with a stem cell transplant, especially if other treatments have not worked. Except for biopsy and staging, surgery is rarely used to treat the condition.
Several major pharma and biotech companies are developing therapies for Hodgkin’s Lymphoma. Currently, Affimed Therapeutics is leading the therapeutics market with its Hodgkin’s Lymphoma drug candidates in the mid to advanced stage of clinical development.
Hodgkin’s Lymphoma Companies Actively Working in the Therapeutics Market Include
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Affimed Therapeutics
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ACD Therapeutics
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Cstone Pharmaceuticals
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4SC
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TG Therapeutics
And Many Other
Emerging and Marketed Hodgkin’s Lymphoma Therapies Covered in the Report Include:
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AFM 13: Affimed Therapeutics
Affimed Therapeutics’ new drug candidate, AFM 13, is a type of immunotherapy, currently in the development stage for the treatment of Hodgkin’s disease. Phase I data demonstrated good efficacy and tolerability. The drug has been designated with orphan drug status. The drug does not kill cancer cells directly but encourages the body’s own immune system to seek out and destroy the cells. It works by activating a type of immune cell, called a natural killer (NK) cell, and directing them to destroy the cancerous cells.
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Camidanlumab tesirine: ACD Therapeutics
ACD Therapeutics’ “breakthrough” drug carnidanlumab tesirine is currently being evaluated for the treatment of Hodgkin’s lymphoma and has demonstrated safety and efficacy in phase I trials. It is an antibody-drug conjugate against CD25 expressed on the surface of cancerous cells.
Similarly, other major players, which are expected to enter the Hodgkin Lymphoma market in the coming years include BeiGene (Tislelizumab), Tessa Therapeutics (Autologous CD30), and others. The launch of these therapies is expected in the near future.
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Table of Content (TOC)
1. Key Insights
2. Executive Summary
3. Hodgkin’s Lymphoma Competitive Intelligence Analysis
4. Hodgkin’s Lymphoma Market Overview at a Glance
5. Hodgkin’s Lymphoma Disease Background and Overview
6. Hodgkin’s Lymphoma Patient Journey
7. Hodgkin’s Lymphoma Patient Population and Epidemiology Trends (In the US, EU5, and Japan)
8. Hodgkin’s Lymphoma Treatment Algorithm, Current Treatment, and Medical Practices
9. Hodgkin’s Lymphoma Unmet Needs
10. Key Endpoints of Hodgkin’s Lymphoma Treatment
11. Hodgkin’s Lymphoma Marketed Therapies
12. Hodgkin’s Lymphoma Emerging Drugs and Latest Therapeutic Advances
13. Hodgkin’s Lymphoma Seven Major Market Analysis
14. Attribute Analysis
15. Hodgkin’s Lymphoma Market Outlook (In US, EU5, and Japan)
16. Hodgkin’s Lymphoma Companies Active in the Market
17. Hodgkin’s Lymphoma Access and Reimbursement Overview
18. KOL Views on the Hodgkin’s Lymphoma Market
19. Hodgkin’s Lymphoma Market Drivers
20. Hodgkin’s Lymphoma Market Barriers
21. Appendix
22. DelveInsight Capabilities
23. Disclaimer
*The Table of Contents (TOC) is not exhaustive; the final content may vary. Refer to the sample report for the complete table of contents.
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About DelveInsight
DelveInsight is a leading Business Consultant and Market Research Firm focused exclusively on life sciences. It supports pharma companies by providing comprehensive end-to-end solutions to improve their performance.
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