DelveInsight’s “High-grade Glioma Market Insights, Epidemiology, and Market Forecast-2032″ report offers an in-depth understanding of the High-grade Glioma, historical and forecasted epidemiology as well as the High-grade Glioma market trends in the United States, EU4 (Germany, Spain, Italy, France) the United Kingdom and Japan.

To Know in detail about the High-grade Glioma market outlook, drug uptake, treatment scenario and epidemiology trends, Click here; High-grade Glioma Market Forecast

Some of the key facts of the High-grade Glioma Market Report: 

• The High-grade Glioma market size was valued approximately USD 1.4 billion in 2022 and is anticipated to grow with a significant CAGR during the study period (2019-2032)

• In November 2023, BioMimetix revealed that its BMX-001, when administered alongside radiotherapy and temozolomide, extended the median survival of glioma patients by 6.6 months. Moreover, this treatment combination mitigated radiation-induced cognitive impairments and enhanced the integrity of white matter. These outcomes stem from the Phase II study (NCT02655601) conducted by the clinical-stage biotech, focusing on evaluating the candidate in patients with high-grade glioma (HGG).

• The collective number of new cases of high-grade glioma (HGG) in the seven main markets was approximately 35,000 in 2022, with expectations of a rise over the study duration.

• Some of the most hopeful upcoming medications in the high-grade glioma (HGG) developmental pipeline include Eflornithine, Regorafenib, Ofranergene, Obadenovec, AV-GBM-1, Tasadenoturev, VAL-083, ONC201, Selinexor, VBI-1901, Paxalisib, MDNA55, ITI-1000, and the combination of INO-5401, INO-9012, and Cemiplimab.

• Throughout the research period from 2019 to 2032, the United States holds the largest market share for high-grade glioma (HGG), surpassing the combined market sizes of the EU4 countries, the UK, and Japan. In 2022 alone, the market size in the United States was estimated to exceed USD 900 million.

• Key High-grade Glioma Companies: Everfront Biotech Co., Ltd., BioMimetix JV, LLC, Chimerix, Laminar Pharmaceuticals, Nationwide Children’s Hospital, Rigel Pharmaceuticals, Orbus Therapeutics, BioMimetix, Bayer, MedImmune, DNAtrix, Chimerix, CNS Pharmaceuticals, VBI Vaccines, Kazia Therapeutics, Aivita Biomedical, Medicenna Therapeutics, DelMar Pharmaceuticals, Bristol-Myers Squibb, Laminar Pharmaceuticals, Immunomic Therapeutics, Inovio Pharmaceuticals, and others

• Key High-grade Glioma Therapies: Cerebraca wafer, BMX-001, ONC201, LAM561, Ribociclib, Olutasidenib + TMZ, Eflornithine + Lomustine, BMX-001, Regorafenib, Durvalumab (MEDI4736), Tasadenoturev (DNX-2401), ONC201, Berubicin, VBI-1901, Paxalisib (GDC-0084), AV-GBM-1, MDNA55, VAL-083 (Dianhydrogalactitol), Pomalidomide, LP561A1 (2-OHOA), ITI-1000 (pp65 DC Vaccine), INO-5401+ INO-9012+ Cemiplimab (REGN2810), and others

• The High-grade Glioma epidemiology based on gender analyzed that High-grade Glioma is more common in men than in women

• The High-grade Glioma market is expected to surge due to the disease’s increasing prevalence and awareness during the forecast period. Furthermore, launching various multiple-stage High-grade Glioma pipeline products will significantly revolutionize the High-grade Glioma market dynamics.

High-grade Glioma Overview

High-grade glioma (HGG) refers to a group of aggressive brain tumors that arise from glial cells, which are supportive cells in the brain and spinal cord. These tumors are characterized by their rapid growth and tendency to invade surrounding brain tissue. High-grade gliomas are classified as grade III or grade IV tumors based on their histological features and aggressiveness.

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High-grade Glioma Epidemiology

The epidemiology section provides insights into the historical, current, and forecasted epidemiology trends in the seven major countries (7MM) from 2019 to 2032. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. The epidemiology section also provides a detailed analysis of the diagnosed patient pool and future trends.

High-grade Glioma Epidemiology Segmentation:

The High-grade Glioma market report proffers epidemiological analysis for the study period 2019–2032 in the 7MM segmented into:

• Total Prevalence of High-grade Glioma

• Prevalent Cases of High-grade Glioma by severity

• Gender-specific Prevalence of High-grade Glioma

• Diagnosed Cases of Episodic and Chronic High-grade Glioma

Download the report to understand which factors are driving High-grade Glioma epidemiology trends @ High-grade Glioma Epidemiology Forecast

High-grade Glioma Drugs Uptake and Pipeline Development Activities

The drugs uptake section focuses on the rate of uptake of the potential drugs recently launched in the High-grade Glioma market or expected to get launched during the study period. The analysis covers High-grade Glioma market uptake by drugs, patient uptake by therapies, and sales of each drug. 

Moreover, the therapeutics assessment section helps understand the drugs with the most rapid uptake and the reasons behind the maximal use of the drugs. Additionally, it compares the drugs based on market share.

The report also covers the High-grade Glioma Pipeline Development Activities. It provides valuable insights about different therapeutic candidates in various stages and the key companies involved in developing targeted therapeutics. It also analyzes recent developments such as collaborations, acquisitions, mergers, licensing patent details, and other information for emerging therapies.

High-grade Glioma Therapies and Key Companies

• Cerebraca wafer: Everfront Biotech Co., Ltd.

• BMX-001: BioMimetix JV, LLC

• ONC201: Chimerix

• LAM561: Laminar Pharmaceuticals

• Ribociclib: Nationwide Children’s Hospital

• Olutasidenib + TMZ: Rigel Pharmaceuticals

• Eflornithine + Lomustine: Orbus Therapeutics

• BMX-001: BioMimetix

• Regorafenib: Bayer

• Durvalumab (MEDI4736): MedImmune

• Tasadenoturev (DNX-2401): DNAtrix

• ONC201: Chimerix

• Berubicin: CNS Pharmaceuticals

• VBI-1901: VBI Vaccines

• Paxalisib (GDC-0084): Kazia Therapeutics

• AV-GBM-1: Aivita Biomedical

• MDNA55: Medicenna Therapeutics

• VAL-083 (Dianhydrogalactitol): DelMar Pharmaceuticals

• Pomalidomide: Bristol-Myers Squibb

• LP561A1 (2-OHOA): Laminar Pharmaceuticals

• ITI-1000 (pp65 DC Vaccine): Immunomic Therapeutics

• INO-5401+ INO-9012+ Cemiplimab (REGN2810): Inovio Pharmaceuticals

Discover more about therapies set to grab major High-grade Glioma market share @ High-grade Glioma Treatment Landscape

High-grade Glioma Market Strengths

• Rise in HGG market is attributed to several factors such as aging population, evolving research, more diagnostic tests, developing surgical approaches, improved radio therapy techniques and novel systemic therapies.

• Improvement in genomics and proteomics can lead to an acceleration in the discovery of novel treatment and drug deliverance.

High-grade Glioma Market Opportunities

• Increasing incidence trend will provide better therapeutic approaches for the HGG market in the near future.

• The market of High-grade Glioma is currently using Temozolomide and Evacizumab as approved therapies, but the market lacks an effective strategy to cure HGG, which provides a lucrative opportunity to develop more treatment options.

Scope of the High-grade Glioma Market Report

• Study Period: 2019–2032

• Coverage: 7MM [The United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan]

• Key High-grade Glioma Companies: Everfront Biotech Co., Ltd., BioMimetix JV, LLC, Chimerix, Laminar Pharmaceuticals, Nationwide Children’s Hospital, Rigel Pharmaceuticals, Orbus Therapeutics, BioMimetix, Bayer, MedImmune, DNAtrix, Chimerix, CNS Pharmaceuticals, VBI Vaccines, Kazia Therapeutics, Aivita Biomedical, Medicenna Therapeutics, DelMar Pharmaceuticals, Bristol-Myers Squibb, Laminar Pharmaceuticals, Immunomic Therapeutics, Inovio Pharmaceuticals, and others

• Key High-grade Glioma Therapies: Cerebraca wafer, BMX-001, ONC201, LAM561, Ribociclib, Olutasidenib + TMZ, Eflornithine + Lomustine, BMX-001, Regorafenib, Durvalumab (MEDI4736), Tasadenoturev (DNX-2401), ONC201, Berubicin, VBI-1901, Paxalisib (GDC-0084), AV-GBM-1, MDNA55, VAL-083 (Dianhydrogalactitol), Pomalidomide, LP561A1 (2-OHOA), ITI-1000 (pp65 DC Vaccine), INO-5401+ INO-9012+ Cemiplimab (REGN2810), and others

• High-grade Glioma Therapeutic Assessment: High-grade Glioma current marketed and High-grade Glioma emerging therapies

• High-grade Glioma Market Dynamics: High-grade Glioma market drivers and High-grade Glioma market barriers 

• Competitive Intelligence Analysis: SWOT analysis, PESTLE analysis, Porter’s five forces, BCG Matrix, Market entry strategies

• High-grade Glioma Unmet Needs, KOL’s views, Analyst’s views, High-grade Glioma Market Access and Reimbursement 

To know more about High-grade Glioma companies working in the treatment market, visit @ High-grade Glioma Clinical Trials and Therapeutic Assessment

Table of Contents 

1. High-grade Glioma Market Report Introduction

2. Executive Summary for High-grade Glioma

3. SWOT analysis of High-grade Glioma

4. High-grade Glioma Patient Share (%) Overview at a Glance

5. High-grade Glioma Market Overview at a Glance

6. High-grade Glioma Disease Background and Overview

7. High-grade Glioma Epidemiology and Patient Population

8. Country-Specific Patient Population of High-grade Glioma 

9. High-grade Glioma Current Treatment and Medical Practices

10. High-grade Glioma Unmet Needs

11. High-grade Glioma Emerging Therapies

12. High-grade Glioma Market Outlook

13. Country-Wise High-grade Glioma Market Analysis (2019–2032)

14. High-grade Glioma Market Access and Reimbursement of Therapies

15. High-grade Glioma Market Drivers

16. High-grade Glioma Market Barriers

17.  High-grade Glioma Appendix

18. High-grade Glioma Report Methodology

19. DelveInsight Capabilities

20. Disclaimer

21. About DelveInsight

About DelveInsight 

DelveInsight is a leading Healthcare Business Consultant, and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance.

It also offers Healthcare Consulting Services, which benefits in market analysis to accelerate the business growth and overcome challenges with a practical approach.

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