Dr. Amr Mohamed Explains the Influence Of Gut Microbiome on Kidney Health

Dr. Amr Mohamed is a kidney doctor in Kentucky. Otherwise known as a nephrologist, Dr. Amr Mohamed helps patients with poor kidney health. He also informs patients how to take care of themselves to reduce the likelihood of kidney disease in the future. 

Of the many things patients can do to decrease the probability of kidney disease, one of the things that makes the most difference is considering the gut microbiome and its impact on renal function and the body as a whole. 

“Gut microbiome is one of the largest and most important organs in our body,” says Dr. Amr Mohamed. 

“There is continuous dialogue and cross-talks between the gut microbiome and other human organs. It affects our quality of life and life-span as well.” 

Dr. Amr Mohamed says that there is growing evidence that chronic kidney disease induces dysbiosis, which is an abnormal change in the gut microbial diversity. Not only does this affect the health outcome of renal patients, but it affects the entire body. 

“The relationship between kidney diseases and dysbiosis is bidirectional; gut-derived metabolites and toxins can cause rapid loss of kidney function, and the uremic milieu has a bad impact on gut microbiota.”

“Moreover, polypharmacy, which is not uncommon in patients, with kidney diseases can negatively affect the gut microbiota. Reno protective metabolites such as bile and short-chain fatty acids may help to delay the progression of chronic kidney disease,” says Dr. Amr Mohamed. 

For this reason. Dr. Amr Mohamed strongly recommends taking care of your overall health, gut microbiome and kidney health as easrly as possible to reduce the need for polypharmacy. 

“We are what we eat and our dietary habits alter the gut microbiome. In patients with normal kidney function there are several adaptive mechanisms that alleviate the need to protect our body from toxins and injurious substances.” 

“Patients with low kidney function lose the compensatory and adaptive processes and start to have maladaptive procedures that usually have bad consequences. Low animal protein and eating more vegetables and fruits that have high-fibers improves the gut microbiota environment.”

Dr. Amr Mohamed says that patients with chronic kidney disease also tend to have altered urinary microbiomes, which increases the susceptibility of urine infections and induces antibiotic resistance.

Recent research has shown that probiotics, which are live microorganisms that provide health benefits to people when consumed in adequate amounts, may also play a role in improving kidney health. 

A systematic review of randomized controlled trials found that probiotic supplementation improved several markers of kidney function in patients with chronic kidney disease. More studies, however, are needed to confirm these findings and determine the optimal type, dose, and duration of probiotic supplementation.

It is worth noting that the gut microbiome is a complex and dynamic ecosystem, and there is still a lot to learn about its role in kidney health. By paying attention to gut health and our diet, incorporating healthy lifestyle changes, and potentially adding probiotic supplementation, patients with kidney disease may be able to improve their overall health outcomes.

In conclusion, as Dr. Amr Mohamed emphasizes, taking care of the gut microbiome is an important aspect of kidney health. By making dietary and lifestyle changes that promote a healthy gut microbiota environment, patients may be able to reduce the risk of complications from kidney disease. As Dr. Mohamed puts it, “Nothing is better than saving people’s lives.”

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