New York, US–May 22, 2019 Creative Biolabs, a leading service supplier in recombinant antibody discovery and manufacturing, is capable of offering a comprehensive list of MHC tetramer products to help its worldwide customers with their immunotherapy research about a host of diseases, such as caners and infections. Simultaneously, the company also provides related custom services to better fulfill the diversified market demands.
The major histocompatibility complex (MHC) represents genes that code for cell surface proteins critical for the immune system to recognize alien molecules, which determines histocompatibility. The MHC tetramer is a type of immunological reagents, composed of four MHC complexes and monomer molecules binding antigenic peptides. When marked with fluorescence, it can be used for MHC tetramer assay in T cell immunoassay. Moreover, the MHC tetramer has a broad application prospect in the study of viral infections, tumors, autoimmune diseases and the screening of the dominant epitope of antigen-peptide immunity.
“As a pioneer in research and development of MHC tetramers, our company has produced a wide range of related products for research about diseases. In immunotherapy, MHC tetramers enable the ex vivo selection and proliferation of T cells specific to tumor-related antigens, which can strengthen the human immunity when going back to the body. Recent studies also showed that MHC tetramers can detect and characterize the rare antigen-specific CD8+ T-cell populations. This may as well impact vaccine development, leading to the production of more effective therapeutic antibodies,” said a scientist from Creative Biolabs.
“T cells play a key role in regulating the immune system to resist foreign invaders, such as viruses and bacteria. MHC tetramers are quite effective in recognizing antigen-specific T cells. Thus, it matters a great deal to produce excellent MHC tetramer products. In this respect, we have abundant experience and numerous successful cases. At present, many of our tetramer products are popular in the market, such as EGFR, ERBB2, HIV-1 gp41 and tetanus toxin. In response to our customers’ different requirements, we offer tailored services as an alternative.”
In immunology, the MHC tetramer displays an extraordinary potential for the diagnosis and treatment of many diseases. Besides, it’s conducive to the development of antibody products, such as vaccines. At its initial development stage, MHC tetramers still have a long way to go. Given the fast progress of medical science and technology, it’s predictable that in the near future they will be applied broadly to many more research areas of immunology.
About Creative Biolabs
Creative Biolabs, a company located in New York, is committed to providing its global customers with the most comprehensive range of recombinant antibody products and extensive service portfolio at the most competitive price. Its products range from antibody/peptide libraries, biosimilar cell lines, chimeric antigen receptor (CDR) products, antibody-drug conjugates (ADC) to engineered antibodies. It also provides a variety of custom antibody discovery and engineering services.
Company Name: Creative Biolabs
Contact Person: Candy Swift
Email: Send Email
Address:45-1 Ramsey Road
State: New York
Country: United States