New York, April 25, 2019 Creative Biolabs, a world-leading antibody provider, now offers highly specific anti SRC antibody and TSH receptor antibody applied to the thyroid cancer research for scientists and researchers all over the world.
With an steadily increasing incidence and mortality over the last four decades, thyroid cancer (TC) remains the most common endocrine malignancy worldwide, commonly diagnosed at a younger age than most other adult cancers, of which the development, progression, invasion, and metastasis are closely associated with multiple signaling pathways and the functions of related molecules, such as SRC, thyroid stimulating hormone receptor (TSHR) signaling pathways. In order to better control the inhibition and activation activity of these signaling pathways, anti SRC antibody and TSH receptor antibody are developed by Creative Biolabs for a more comprehensive thyroid cancer research.
The protein encoded by TSHR is a membrane protein and a major controller of thyroid cell metabolism. Defects of TSHR are closely related with hyperthyroidism with different etiologies and thyroid neoplasms (papillary and follicular cancers). The mutations lead to TSH independent activation of the cAMP cascade resulting in thyroid growth and hormone production. Three transcript variants encoding different isoforms have been found for this gene. Antibody interaction with TSHR can contribute to an uncontrolled receptor stimulation.
Cooperated with PTK2B, anti SRC antibody makes an effective impression in osteoclastic bone resorption, which requires both the formation of SRC-PTK2B complex, and SRC kinase activity. The antibody also plays a role in inducing the activation and recruitment of phosphatidylinositol 3-kinase to the cell membrane and promoting energy production in osteoclasts by activating mitochondrial cytochrome C oxidase.
Based on a comprehensive antibody platform, Creative Biolabs can provide high-quality antibodies for cancer research, which are strictly verified by ICC, IHC, WB, FACS.
- Low endotoxin levels and High purity
- Strictly verified by ICC, IHC, WB, FACS
- High specificity and reproducibility
- Performance 100% Guaranteed
In addition to antibodies for thyroid cancer research, there are a variety of antibodies available for the research of other diseases and cancers. More detailed information can be reached at https://www.antibody-creativebiolabs.com.
Since 2004, Creative Biolabs has been dedicated to providing high-quality services to the academic and life sciences worldwide. In the past decade, Creative Biolabs become the leader in the discovery and manufacture of recombinant antibodies. A custom-service-centered business model is crucial for optimizing the drug development process, leveraging accessible resources, and gathering a team from various backgrounds to conduct drug discovery projects in the future. As the preferred supplier for global customers, scientists in Creative Biolabs are confident to provide customers with first-class services covering a full range of applications.
Company Name: Creative Biolabs
Contact Person: Candy Swift
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Address:45-1 Ramsey Road
State: New York
Country: United States