The Congenital Hyperinsulinism market report covers emerging drugs, current treatment practices, market share of the individual therapies, current and forecasted market size from 2019 to 2032. It also evaluates the current treatment practice/algorithm, market drivers & barriers, and unmet medical needs to curate the best of the opportunities and assess the underlying potential of the market.
Congenital Hyperinsulinism: An Overview
Congenital hyperinsulinism (CHI) is a condition that causes individuals to have abnormally high levels of insulin, which is a hormone that helps control blood sugar levels. People with this condition have frequent occurrences of low blood sugar (hypoglycemia). In infants and young children, these occurrences are characterized by a lack of energy (lethargy), irritability, or difficulty feeding. Repeated episodes of low blood sugar increase the risk for serious complications such as breathing difficulties, seizures, intellectual disability, vision loss, brain damage, and coma.
The severity of Congenital Hyperinsulinism varies widely among affected individuals, even among members of the same family. About 60% of infants with this condition experience a hypoglycemic episode within the first month of life. Other affected children develop hypoglycemia by early childhood.
Congenital Hyperinsulinism Market Key Facts
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According to DelveInsight, the total Congenital Hyperinsulinism prevalent population in the 7 major markets was estimated to be 21,800+ cases in 2017, which is expected to increase by 2032.
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Among the EU5 countries, Germany had the highest prevalent population of Congenital Hyperinsulinism with 2,300+ cases in 2017, followed by UK and France. On the other hand, Spain had the lowest prevalent population.
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In 2017, the total Congenital Hyperinsulinism prevalent population in the United States was found to be 9,700+.
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According to the National Institute of Health, CHI affects approximately 1 in 50,000 newborns. This condition is more common in certain populations, affecting up to 1 in 2,500 newborns.
Congenital Hyperinsulinism Market
The Congenital Hyperinsulinism (CHI) Market Size is expected to increase in the coming years owing to the rise in the prevalent cases of Congenital Hyperinsulinism in the 7MM.
The market outlook section of the report helps to build a detailed comprehension of the historic, current, and forecasted Congenital Hyperinsulinism market size by analyzing the impact of current and emerging therapies in the market. It also provides a detailed assessment of the market drivers & barriers, unmet needs, and emerging technologies.
The report gives a thorough detail of the Congenital Hyperinsulinism market trend for each marketed drug and late-stage pipeline therapies by evaluating their impact based on the annual cost of therapy, inclusion and exclusion criteria, mechanism of action (MoA), competition with other therapies, brand value, their impact on the market and view of the key opinion leaders.
Congenital Hyperinsulinism Epidemiology
The epidemiology section covers insights into the historical and current Congenital Hyperinsulinism patient pool and forecasted trends for every seven major countries (7MM) from 2019 to 2032. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. The epidemiology section also provides the diagnosed patient pool and their trends along with assumptions undertaken.
Congenital Hyperinsulinism Epidemiology Segmentation –
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Total Prevalent Cases of Congenital Hyperinsulinism (CHI)
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Diagnosed and Treatable Cases of Congenital Hyperinsulinism (CHI)
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Type-specific Diagnosed Prevalent Cases of Congenital Hyperinsulinism
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Mutation-specific Diagnosed Prevalent Cases of Congenital Hyperinsulinism (CHI) {ABCC8, KCNJ11, and others}
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Subtype-specific Diagnosed Prevalent Cases of Congenital Hyperinsulinism(CHI) based on histology
Congenital Hyperinsulinism Drugs Uptake and Pipeline Development Activities
The drugs uptake section focuses on the rate of uptake of the potential drugs recently launched in the Congenital Hyperinsulinism market or expected to get launched in the market during the study period. The analysis covers Congenital Hyperinsulinism market uptake by drugs; patient uptake by therapies; and sales of each drug.
Report’s Drugs Uptake section helps in understanding the drugs with the most rapid uptake, reasons behind the maximal use of new drugs and allows the comparison of the drugs on the basis of market share and size which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.
The report also covers the Congenital Hyperinsulinism Pipeline Development Activities and provides valuable insights about different therapeutic candidates in Phase II, and Phase III stages and the key companies in the market involved in developing targeted therapeutics. It also analyses the recent Development such as collaborations, acquisitions, and mergers, licensing patent details, and other information for emerging therapies.
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Congenital Hyperinsulinism Therapeutics Analysis
The Congenital Hyperinsulinism market dynamics is anticipated to change in the coming years owing to the improvement in the research and development activities so that market will comprise efficient treatment options.
Some of the key companies in the Congenital Hyperinsulinism Market include-
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Rezolute
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Zealand Pharma
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Xeris Pharmaceuticals
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Eiger BioPharmaceuticals
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AmideBio and Recordati
And many others.
Congenital Hyperinsulinism Therapies covered in the report include:
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RZ358
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CSI-Glucagon
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Avexitide
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Dasiglucagon
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Pasireotide (Signifor)
And many more.
The congenital Hyperinsulinism (CHI) pipeline is not robust, however, it possesses promising and potential drugs in the clinical stage of development, which are expected to be launched in the near future.
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Table of Content (TOC)
1. Key Insights
2. Executive Summary
3. Congenital Hyperinsulinism Competitive Intelligence Analysis
4. Congenital Hyperinsulinism Market Overview at a Glance
5. Congenital Hyperinsulinism Disease Background and Overview
6. Congenital Hyperinsulinism Patient Journey
7. Congenital Hyperinsulinism Epidemiology and Patient Population
8. Congenital Hyperinsulinism Treatment Algorithm, Current Treatment, and Medical Practices
9. Congenital Hyperinsulinism Unmet Needs
10. Key Endpoints of Congenital Hyperinsulinism Treatment
11. Congenital Hyperinsulinism Marketed Products
12. Congenital Hyperinsulinism Emerging Therapies
13. Congenital Hyperinsulinism Seven Major Market Analysis
14. Attribute Analysis
15. Congenital Hyperinsulinism Market Outlook (7 major markets)
16. Congenital Hyperinsulinism Access and Reimbursement Overview
17. KOL Views on the Congenital Hyperinsulinism Market.
18. Congenital Hyperinsulinism Market Drivers
19. Congenital Hyperinsulinism Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer
*The Table of Contents (TOC) is not exhaustive; the final content may vary. Refer to the sample report for the complete table of contents.
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About DelveInsight
DelveInsight is a leading Business Consultant, and Market Research Firm focused exclusively on life sciences. It supports pharma companies by providing end-to-end comprehensive solutions to improve their performance.
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