DelveInsight reports that over three key companies are actively involved in the development of three or more therapeutic candidates targeting chronic wounds, reflecting a steady pipeline in this treatment area.
Chronic Wounds Overview:
A chronic wound is one that fails to progress through the normal stages of healing in a timely and structured manner, typically not healing within a three-month period. These wounds—often classified as ulcers—involve full-thickness tissue damage and are slow to recover. Common types include non-healing surgical or traumatic wounds, venous ulcers, pressure ulcers, diabetic foot ulcers, and ischemic ulcers. They are generally grouped into vascular ulcers, diabetic ulcers, and pressure ulcers.
Chronic wounds usually exhibit raised, non-advancing edges, persistent inflammation, and impaired healing. Symptoms may include fever, redness, warmth, pus discharge (milky yellow to brown), swelling, pain, reduced mobility, wound enlargement, and necrotic or dark skin.
Several factors contribute to chronic wound formation, such as diabetes, vascular conditions like peripheral artery disease, limited mobility, repeated trauma, and bacterial infections (e.g., *Staphylococcus aureus*). Key drivers include poor blood circulation, localized pressure, nerve damage, chronic infection, and dysregulated healing mechanisms, including inadequate angiogenesis, cell proliferation, and epithelial repair—all of which can be worsened by uncontrolled conditions like elevated blood glucose at the wound site.
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“Chronic Wounds Pipeline Insight 2025” report by DelveInsight provides a comprehensive analysis of the ongoing clinical development activities and growth prospects across the Chronic Wounds Therapeutics Market.
Key Takeaways from the Chronic Wounds Pipeline Report
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In May 2019, TissueTech received a patent (US9808491B2) from the USPTO for a gel composition containing morselized placental amniotic membrane and umbilical cord, designed for treating ocular wounds and repairing damaged ocular tissue. The patent is set to expire in 2035.
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In May 2022, the U.S. FDA granted Regenerative Medicine Advanced Therapy (RMAT) designation to SkinTE under the company’s active IND application.
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On October 12, 2022, Healthium Medtech, a medical device company, introduced Theruptor Novo, a new wound dressing portfolio aimed at managing chronic wounds, including diabetic foot ulcers and leg ulcers.
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DelveInsight’s Chronic Wounds pipeline report depicts a robust space with 3+ active players working to develop 3+ pipeline therapies for Chronic Wounds treatment.
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Key Chronic Wounds companies such as PolarityTE, Aurealis Therapeutics, Akribes Biomedical, and others are evaluating new drugs for Chronic Wounds to improve the treatment landscape.
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Promising Chronic Wounds pipeline therapies in various stages of development include IO102 SkinTE3, and others.
Chronic Wounds Pipeline Analysis
The report provides insights into:
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The report provides detailed insights into the key companies that are developing therapies in the Chronic Wounds Market.
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The report also evaluates different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Chronic Wounds treatment.
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It analyzes the key companies involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
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It navigates the emerging drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.
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Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement, and financing details for future advancement of the Chronic Wounds market.
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Chronic Wounds Emerging Drugs
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SkinTE: PolarityTE
Chronic Wounds Companies
Over three major companies are actively engaged in developing treatments for chronic wounds. Among these, PolarityTE leads with its most advanced drug candidates currently progressing through Phase III clinical trials.
DelveInsight’s report covers around 3+ products under different phases of clinical development like
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Late stage products (Phase III)
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Mid-stage products (Phase II)
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Early-stage product (Phase I) along with the details of
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Pre-clinical and Discovery stage candidates
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Discontinued & Inactive candidates
Chronic Wounds pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
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Intravenous
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Subcutaneous
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Oral
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Intramuscular
Chronic Wounds Products have been categorized under various Molecule types such as
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Monoclonal antibody
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Small molecule
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Peptide
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Chronic Wounds Pipeline Therapeutic Assessment
• Chronic Wounds Assessment by Product Type
• Chronic Wounds By Stage
• Chronic Wounds Assessment by Route of Administration
• Chronic Wounds Assessment by Molecule Type
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Table of Content
1. Report Introduction
2. Executive Summary
3. Chronic Wounds Current Treatment Patterns
4. Chronic Wounds – DelveInsight’s Analytical Perspective
5. Therapeutic Assessment
6. Chronic Wounds Late-Stage Products (Phase-III)
7. Chronic Wounds Mid-Stage Products (Phase-II)
8. Early Stage Products (Phase-I)
9. Pre-clinical Products and Discovery Stage Products
10. Inactive Products
11. Dormant Products
12. Chronic Wounds Discontinued Products
13. Chronic Wounds Product Profiles
14. Chronic Wounds Key Companies
15. Chronic Wounds Key Products
16. Dormant and Discontinued Products
17. Chronic Wounds Unmet Needs
18. Chronic Wounds Future Perspectives
19. Chronic Wounds Analyst Review
20. Appendix
21. Report Methodology
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