Chronic Lymphocytic Leukemia Pipeline, FDA Approvals, Clinical Trials Developments, and Companies 2023 | Loxo Oncology, Oncternal Therapeutics, MingSight Pharmaceuticals, Nurix Therapeutics and Others

Chronic Lymphocytic Leukemia Pipeline, FDA Approvals, Clinical Trials Developments, and Companies 2023 | Loxo Oncology, Oncternal Therapeutics, MingSight Pharmaceuticals, Nurix Therapeutics and Others

DelveInsight’s, “Chronic Lymphocytic Leukemia Pipeline Insight 2023,” report provides comprehensive insights about 55+ companies and 60+ pipeline drugs in Chronic Lymphocytic Leukemia pipeline landscape. It covers the Chronic Lymphocytic Leukemia pipeline drug profiles, including clinical and nonclinical stage products. It also covers the Chronic Lymphocytic Leukemia pipeline therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

 

Key Takeaways from the Chronic Lymphocytic Leukemia Pipeline Report

  • DelveInsight’s Chronic Lymphocytic Leukemia pipeline report depicts a robust space with 55+ active players working to develop 60+ pipeline therapies for Chronic Lymphocytic Leukemia treatment.
  • The leading companies working in the Chronic Lymphocytic Leukemia Market include Loxo Oncology, Oncternal Therapeutics, MingSight Pharmaceuticals, Nurix Therapeutics, Starton Therapeutics, TG therapeutics, Bristol Myers Squibb, Novartis, Aprea Therapeutics, AstraZeneca, Genor Biopharma, Incyte Corporation, MorphoSys, Astex Therapeutics, Lava Therapeutics, Celgene Corporation, and others.
  • Promising Chronic Lymphocytic Leukemia Pipeline Therapies in the various stages of development include Acalabrutinib, ABT-263, Bendamustine, Venetoclax, Rituximab, FCR, and others.
  • December 2023: Janssen Research & Development Inc. announced a study of Phase 3 clinical trials for Ibrutinib and Venetoclax. The purpose of this study is to assess progression-free survival (PFS) from treatment with ibrutinib plus venetoclax (I+VEN) compared with obinutuzumab plus chlorambucil (G-Clb) as assessed by an Independent Review Committee (IRC).
  • December 2023: Acerta Pharma BV announced a study of Phase 3 clinical trials for Acalabrutinib and Ibrutinib. This study is designed to evaluate progression-free survival (PFS) endpoint for acalabrutinib versus (vs) ibrutinib in previously treated chronic lymphocytic leukemia.
  • June 2023: AbbVie announced a study of Phase 1 & 2 Clinical Trials for ABT-263. The Phase 1 portion of the study will evaluate the pharmacokinetic profile and safety of ABT-263 under two different dosing schedules with the objective of defining the dose limiting toxicity and maximum tolerated dose.
  • July 2023: AstraZeneca announced a study of Phase 3 Clinical Trials for Acalabrutinib. This is a global, Phase 3b, multicenter, open-label, single-arm study to evaluate the safety and efficacy of acalabrutinib 100 mg twice daily (bid) in approximately 540 participants with chronic lymphocytic leukemia (CLL).

 

Request a sample and discover the recent advances in Chronic Lymphocytic Leukemia Treatment Drugs @ Chronic Lymphocytic Leukemia Infection Pipeline Report

 

The Chronic Lymphocytic Leukemia pipeline report provides detailed profiles of pipeline assets, a comparative analysis of clinical and non-clinical stage Chronic Lymphocytic Leukemia drugs, inactive and dormant assets, a comprehensive assessment of driving and restraining factors, and an assessment of opportunities and risks in the Chronic Lymphocytic Leukemia clinical trial landscape.

 

Chronic Lymphocytic Leukemia Overview

Chronic lymphocytic leukemia (CLL) is a malignancy of CD5+ B cells that is characterized by the accumulation of small, mature-appearing neoplastic lymphocytes in the blood, bone marrow, and secondary lymphoid tissues, resulting in lymphocytosis, leukemia cell infiltration of the bone marrow, lymphadenopathy, and splenomegaly. The exact etiology of CLL is unknown.

 

Find out more about Chronic Lymphocytic Leukemia Treatment Landscape @ Drugs for Chronic Lymphocytic Leukemia Treatment

 

Chronic Lymphocytic Leukemia Emerging Drugs Profile

  • Pirtobrutinib: Loxo Oncology
  • Cirmtuzumab: Oncternal Therapeutics
  • MS-553: MingSight Pharmaceuticals
  • NX-2127: Nurix Therapeutics
  • NX-5948: Nurix Therapeutics

 

Chronic Lymphocytic Leukemia Pipeline Therapeutics Assessment

There are approx. 55+ key companies which are developing the therapies for chronic lymphocytic leukemia. The Chronic Lymphocytic Leukemia companies which have their chronic lymphocytic leukemia drug candidates in the most advanced stage, i.e. phase III include, Loxo Oncology.

 

 DelveInsight’s Chronic Lymphocytic Leukemia pipeline report covers around 60+ products under different phases of clinical development like

  • Late stage products (Phase III)
  • Mid-stage products (Phase II)
  • Early-stage product (Phase I) along with the details of
  • Pre-clinical and Discovery stage candidates
  • Discontinued & Inactive candidates

 

Chronic lymphocytic leukemia pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as

  • Intravenous
  • Subcutaneous
  • Oral
  • Intramuscular

 

Products have been categorized under various Molecule types such as

  • Monoclonal antibody
  • Small molecule
  • Peptide

 

Learn more about the emerging Chronic Lymphocytic Leukemia Pipeline Therapies @ Chronic Lymphocytic Leukemia Clinical Trials Assessment

 

Scope of the Chronic Lymphocytic Leukemia Pipeline Report

  • Coverage- Global
  • Therapeutic Assessment by Product Type: Mono, Combination, Mono/Combination
  • Therapeutic Assessment by Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III
  • Chronic Lymphocytic Leukemia Companies– Loxo Oncology, Oncternal Therapeutics, MingSight Pharmaceuticals, Nurix Therapeutics, Starton Therapeutics, TG therapeutics, Bristol Myers Squibb, Novartis, Aprea Therapeutics, AstraZeneca, Genor Biopharma, Incyte Corporation, MorphoSys, Astex Therapeutics, Lava Therapeutics, Celgene Corporation, and others.
  • Chronic Lymphocytic Leukemia Pipeline Therapies– Acalabrutinib, ABT-263, Bendamustine, Venetoclax, Rituximab, FCR, and others.

 

Dive deep into rich insights for new drugs for Chronic Lymphocytic Leukemia treatment, Visit @ Chronic Lymphocytic Leukemia Market Drivers and Barriers, and Future Perspective

 

Table of Content

  1. Introduction
  2. Executive Summary
  3. Chronic lymphocytic leukemia: Overview
  4. Pipeline Therapeutics
  5. Therapeutic Assessment
  6. Chronic lymphocytic leukemia– DelveInsight’s Analytical Perspective
  7. Late Stage Products (Phase III)
  8. Pirtobrutinib: Loxo Oncology
  9. Drug profiles in the detailed report…..
  10. Mid Stage Products (Phase II)
  11. Cirmtuzumab: Oncternal Therapeutics
  12. Drug profiles in the detailed report…..
  13. Early Stage Products (Phase I)
  14. NX-2127: Nurix Therapeutics
  15. Drug profiles in the detailed report…..
  16. Preclinical and Discovery Stage Products
  17. Drug name: Company name
  18. Drug profiles in the detailed report…..
  19. Inactive Products
  20. Chronic lymphocytic leukemia Key Companies
  21. Chronic lymphocytic leukemia Key Products
  22. Chronic lymphocytic leukemia- Unmet Needs
  23. Chronic lymphocytic leukemia- Market Drivers and Barriers
  24. Chronic lymphocytic leukemia- Future Perspectives and Conclusion
  25. Chronic lymphocytic leukemia Analyst Views
  26. Chronic lymphocytic leukemia Key Companies
  27. Appendix

 

For further information on the Chronic Lymphocytic Leukemia pipeline therapeutics, reach out to Chronic Lymphocytic Leukemia Unmet Needs and Analyst Views

 

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