Chronic Lower Back Pain Pipeline Analysis (2023) Covering Clinical Trials, Emerging Therapies, FDA, EMA, and PMDA Approvals, Competitive Landscape | Mesoblast, Camurus, Persica, CHABiotech, Allodynic

Chronic Lower Back Pain Pipeline Analysis (2023) Covering Clinical Trials, Emerging Therapies, FDA, EMA, and PMDA Approvals, Competitive Landscape | Mesoblast, Camurus, Persica, CHABiotech, Allodynic
Delveinsight Business Research LLP
As per DelveInsight’s assessment, globally, about 10+ key pharma and biotech companies are working on 10+ pipeline drugs in the Chronic Lower Back Pain therapeutics landscape based on different Routes of Administration (ROA), Mechanism of Action (MOA), and molecule types. Several of the therapies are in the advanced stages of clinical development and are expected to launch in the coming years.

Chronic Lower Back Pain Pipeline Insight, 2023” report by DelveInsight outlines a comprehensive assessment of the present clinical/non-clinical development activities and growth prospects across the Chronic Lower Back Pain Market. 

The Chronic Lower Back Pain Pipeline report embraces in-depth commercial, regulatory, and Chronic Lower Back Pain clinical trial assessment of the pipeline products from the pre-clinical developmental phase to the marketed phase. The report also covers a detailed description of the emerging Chronic Lower Back Pain drugs, including the mechanism of action, clinical studies, NDA approvals (if any), and product development activities comprising the technology, collaborations, mergers, acquisition, funding, designations, and other product-related details.

Chronic Lower Back Pain Pipeline Analysis

The report provides insights into: 

  • The report provides detailed insights into the emerging therapies for Chronic Lower Back Pain treatment and the aggregate therapies developed by major pharma companies.

  • It accesses the different Chronic Lower Back Pain therapies segmented into early-stage, mid-stage, and late-stage of clinical development.

  • It outlines the major Chronic Lower Back Pain companies involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.

  • The report evaluates the Chronic Lower Back Pain drugs that are under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type. 

  • It navigates the major collaborations (company-company collaborations and company-academia collaborations), licensing agreements, financing details, data presentation by the pharma giants, and regulatory approval in the Chronic Lower Back Pain therapeutic market.

Chronic Lower Back Pain Therapeutics Landscape

The majority of low back pain is caused by a mechanical etiology, which includes a degenerative disc or joint disease, vertebral fracture, and deformities and occurs in up to 80–90% of patients, while neurogenic, inflammatory, and other less common causes make up the remainder of etiologies. The pharmacologic agents first selected must be focused on the underlying etiology. However, as the pain progresses to a chronic state, a broader approach typically must be taken due to the decreased efficacy of the targeted treatment.

However, if the cause of low back pain is inflammatory, targeted therapy includes treatment with anti‐inflammatory agents. This refers to the early use of non-steroidal anti‐inflammatories (NSAIDs) and treatment with corticosteroids or disease‐modifying antirheumatic drugs (DMARDs) in patients with rheumatoid arthritis or ankylosing spondylitis. Additionally, these disease states have a higher incidence of neuropathic pain and thus may require adjuvant medications that target this specific pain type. Some patients with mechanical low back pain also have increased pain due to spasticity and may benefit from treatment with antispasmodics. 

In addition to pharmacologic treatments, non-pharmacologic treatments including topical heat for acute pain or cognitive behavioral therapy, exercise therapy, spinal manipulation and interdisciplinary rehabilitation for subacute or chronic pain are necessary.

There are approx. 10+ key companies developing therapies for Chronic Lower Back Pain. Currently, Mesoblast is leading the therapeutics market with its Chronic Lower Back Pain drug candidates in the most advanced stage of clinical development.

Chronic Lower Back Pain Companies Actively Working in the Therapeutic Market Include:

  • Mesoblast

  • Eli Lilly and Company

  • Persica Pharmaceuticals

  • CHABiotech

  • Allodynic Therapeutics

  • Stayble Therapeutics

  • Xgene Pharmaceutical

  • Imbrium Therapeutics

  • Camurus

And Many Others

Emerging and Marketed Chronic Lower Back Pain Drugs Covered in the Report Include:

  • MPC-06-ID: Mesoblast

  • PP353: Persica Pharmaceuticals

  • Brixadi (CAM2038/buprenorphine injection depot): Camurus/Braeburn

  • Semdexa (SP-102, dexamethasone sodium phosphate): Scilex Holding

  • AMG0103: AnGes MG, Inc.

And Many Others

Request the Sample PDF to Get a Better Understanding of the Emerging Drugs and Chronic Lower Back Pain Companies Working in the Market @

Analysis of Emerging Chronic Lower Back Pain Therapies by Phases

The report covers the emerging products under different phases of clinical development like –

  • Late-stage products (Phase III)

  • Mid-stage products (Phase II)

  • Early-stage product (Phase I) 

  • Pre-clinical and Discovery stage candidates

  • Discontinued and inactive candidates

Route of Administration

Chronic Lower Back Pain pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as

  • Oral

  • Parenteral

  • Intravitreal

  • Subretinal

  • Topical

Molecule Type

Products have been categorized under various Molecule types such as

  • Monoclonal Antibody

  • Peptides

  • Polymer

  • Small molecule

  • Gene therapy

Learn How the Chronic Lower Back Pain Treatment Outlook will Evolve with the Ongoing Clinical & Commercial Activities in the Therapeutic Market @

Table of Content (TOC)

1. Report Introduction

2. Executive Summary

3. Chronic Lower Back Pain Treatment Patterns

4. Chronic Lower Back Pain – DelveInsight’s Analytical Perspective

5. Therapeutic Assessment

6. Chronic Lower Back Pain Late Stage Products (Phase-III)

7. Chronic Lower Back Pain Mid-Stage Products (Phase-II)

8. Chronic Lower Back Pain Early Stage Products (Phase-I)

9. Pre-clinical Products and Discovery Stage Products

10. Inactive Products

11. Dormant Products

12. Chronic Lower Back Pain Discontinued Products

13. Chronic Lower Back Pain Product Profiles

14. Major Chronic Lower Back Pain Companies in the Market

15. Key Products in the Chronic Lower Back Pain Therapeutics Segment

16. Dormant and Discontinued Products

17. Chronic Lower Back Pain Unmet Needs

18. Chronic Lower Back Pain Future Perspectives

19. Chronic Lower Back Pain Analyst Review  

20. Appendix

21. Report Methodology

*The Table of Contents (TOC) is not exhaustive; the final content may vary. Refer to the sample report for the complete table of contents.

Download Sample PDF to Explore the Key Offerings of the Report @



About DelveInsight

DelveInsight is a leading Business Consultant and Market Research Firm focused exclusively on life sciences. It supports pharma companies by providing comprehensive end-to-end solutions to improve their performance.

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