Atopic Dermatitis Pipeline Insights

Atopic Dermatitis Pipeline constitutes 100+ key companies continuously working towards developing 110+ Atopic Dermatitis treatment therapies, analyzes DelveInsight.

Atopic Dermatitis Overview:

Atopic dermatitis (AD), commonly known as eczema, is a chronic inflammatory skin disorder that often starts in childhood but can affect individuals at any age. It is the most prevalent form of skin inflammation, marked by persistent itching, redness, and rashes. AD is influenced by genetic predisposition, immune system overactivity, allergies, infections, and environmental irritants. Individuals with moderate-to-severe AD often also experience other allergic conditions such as asthma, hay fever, and food sensitivities. It is particularly widespread among children, making it the most common chronic skin condition in that age group.

The onset of AD involves a complex interplay of factors, including a compromised skin barrier, immune system imbalances, IgE-related hypersensitivity, and exposure to environmental triggers. Mutations in the filaggrin gene, which is vital for skin hydration and barrier integrity, have been linked to more severe disease forms. Additionally, an immune shift from Th1 to Th2 cytokine activity and the buildup of immune cells—particularly dendritic cells—contribute to the inflammation seen in AD.

While the precise cause is still not fully understood, AD is believed to stem from a combination of genetic, immunologic, and environmental influences that impair the skin’s barrier function. This results in dry, irritated, and inflamed skin that is highly sensitive to allergens and irritants. Although AD is not infectious, it can cause significant discomfort due to persistent itching and skin lesions.

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“Atopic Dermatitis Pipeline Insight 2025” report by DelveInsight provides a comprehensive analysis of the ongoing clinical development activities and growth prospects across the Atopic Dermatitis Therapeutics Market.

Key Takeaways from the Atopic Dermatitis Pipeline Report

• DelveInsight’s Atopic Dermatitis pipeline report depicts a robust space with 100+ active players working to develop 110+ pipeline therapies for Atopic Dermatitis treatment.

• In April 2025, Dermavant Sciences announced that the U.S. Food and Drug Administration (FDA) has accepted the Supplemental New Drug Application (sNDA) for VTAMA as a topical treatment for atopic dermatitis.

• Key Atopic Dermatitis companies such as Dermavant Sciences, Pfizer, AOBiome, Allakos Inc., E-nitiate Biopharmaceuticals (Hangzhou) Co., Ltd., Eli Lilly and Company, Vanda Pharmaceuticals, Suzhou Connect Biopharmaceuticals, Arcutis Biotherapeutics, Reistone Biopharma Alphyn Biologics, Argenx, Shulov Innovate for Science, Teres Bio, Qurient Co, Sun Pharmaceutical, Merck Sharp & Dohme LLC, Hangzhou Yirui Pharmaceutical Technology Co., Ltd, GI Innovation, AnaptysBio, MC2 therapeutics, Akaal Pharma, Kiniksa Pharmaceuticals, Selection, Intrinsic Medicine, Genome & Company, TWi Biotechnology, and others are evaluating new drugs for Atopic Dermatitis to improve the treatment landscape.

• Promising Atopic Dermatitis pipeline therapies in various stages of development include Tapinarof, Etrasimod, B244, Lirentelimab, QY201: E-nitiate Biopharmaceuticals (Hangzhou) Co., Ltd., and others.

Atopic Dermatitis Pipeline Analysis

The report provides insights into:

• The report provides detailed insights into the key companies that are developing therapies in the Atopic Dermatitis Market.

• The report also evaluates different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Atopic Dermatitis treatment.

• It analyzes the key companies involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.

• It navigates the emerging drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.

• Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement, and financing details for future advancement of the Atopic Dermatitis market.

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Atopic Dermatitis Emerging Drugs

• Tapinarof: Dermavant Sciences

• Etrasimod: Pfizer

• B244: AOBiome

• Lirentelimab: Allakos Inc.

• QY201: E-nitiate Biopharmaceuticals (Hangzhou) Co., Ltd.

Atopic Dermatitis Companies

Over 100 key companies are working on developing therapies for atopic dermatitis. Among them, Dermavant Sciences has drug candidates for atopic dermatitis in the most advanced stage, Phase III.

DelveInsight’s report covers around 110+ products under different phases of clinical development like

• Late stage products (Phase III)

• Mid-stage products (Phase II)

• Early-stage product (Phase I) along with the details of

• Pre-clinical and Discovery stage candidates

• Discontinued & Inactive candidates

Atopic Dermatitis pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as

• Intravenous

• Subcutaneous

• Oral

• Intramuscular

Atopic Dermatitis Products have been categorized under various Molecule types such as

• Monoclonal antibody

• Small molecule

• Peptide

Download Sample Pages to Get an in-depth Assessment of the Emerging Atopic Dermatitis Therapies and Key Companies: Atopic Dermatitis Clinical Trials and advancements

Atopic Dermatitis Pipeline Therapeutic Assessment

• Atopic Dermatitis Assessment by Product Type

• Atopic Dermatitis By Stage

• Atopic Dermatitis Assessment by Route of Administration

• Atopic Dermatitis Assessment by Molecule Type

Download Atopic Dermatitis Sample report to know in detail about the Atopic Dermatitis treatment market @ Atopic Dermatitis Therapeutic Assessment

Table of Content

1. Report Introduction

2. Executive Summary

3. Atopic Dermatitis Current Treatment Patterns

4. Atopic Dermatitis – DelveInsight’s Analytical Perspective

5. Therapeutic Assessment

6. Atopic Dermatitis Late-Stage Products (Phase-III)

7. Atopic Dermatitis Mid-Stage Products (Phase-II)

8. Early Stage Products (Phase-I)

9. Pre-clinical Products and Discovery Stage Products

10. Inactive Products

11. Dormant Products

12. Atopic Dermatitis Discontinued Products

13. Atopic Dermatitis Product Profiles

14. Atopic Dermatitis Key Companies

15. Atopic Dermatitis Key Products

16. Dormant and Discontinued Products

17. Atopic Dermatitis Unmet Needs

18. Atopic Dermatitis Future Perspectives

19. Atopic Dermatitis Analyst Review

20. Appendix

21. Report Methodology

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