Acute Kidney Injury (AKI) Pipeline Analysis (2023) Covering Clinical Trials, Emerging Therapies, FDA, EMA, and PMDA Approvals, Competitive Landscape | Rénibus, Sentien, MediBeacon, Ocelot Bio

Acute Kidney Injury (AKI) Pipeline Analysis (2023) Covering Clinical Trials, Emerging Therapies, FDA, EMA, and PMDA Approvals, Competitive Landscape | Rénibus, Sentien, MediBeacon, Ocelot Bio
Delveinsight Business Research LLP
As per DelveInsight’s assessment, globally, about 30+ key pharma and biotech companies are working on 30+ pipeline drugs in the Acute Kidney Injury therapeutics landscape based on different Routes of Administration (ROA), Mechanism of Action (MOA), and molecule types. Several of the therapies are in the advanced stages of clinical development and are expected to launch in the coming years.

Acute Kidney Injury (AKI) Pipeline Insight, 2023” report by DelveInsight outlines a comprehensive assessment of the present clinical/non-clinical development activities and growth prospects across the Acute Kidney Injury Market. 

The Acute Kidney Injury Pipeline report embraces in-depth commercial, regulatory, and Acute Kidney Injury clinical trial assessment of the pipeline products from the pre-clinical developmental phase to the marketed phase. The report also covers a detailed description of the emerging Acute Kidney Injury drugs, including the mechanism of action, clinical studies, NDA approvals (if any), and product development activities comprising the technology, collaborations, mergers, acquisition, funding, designations, and other product-related details.

Acute Kidney Injury (AKI) Pipeline Analysis

The report provides insights into: 

  • The report provides detailed insights into the emerging therapies for Acute Kidney Injury treatment and the aggregate therapies developed by major pharma companies.

  • It accesses the different Acute Kidney Injury therapies segmented into early-stage, mid-stage, and late-stage clinical development.

  • It outlines the major Acute Kidney Injury companies involved in targeted therapeutics development, with respective active and inactive (dormant or discontinued) projects.

  • The report evaluates the Acute Kidney Injury drugs that are under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type. 

  • It navigates the major collaborations (company-company collaborations and company-academia collaborations), licensing agreements, financing details, data presentation by the pharma giants, and regulatory approval in the Acute Kidney Injury therapeutic market.

Acute Kidney Injury Therapeutics Landscape

For the past several years, it can be observed that the current treatment for AKI is mainly supportive in nature, and no therapeutic modalities to date have shown efficacy in treating the condition. Management of AKI depends on the use of off-label drugs, which includes various drug classes such as ACE inhibitors, angiotensin II-receptor blockers (ARBs), diuretics, nonsteroidal anti-inflammatory drugs (NSAIDs), along with renal replacement therapy (RRT). 

A cornerstone of the management of all patients with AKI is to monitor urine output and initially monitor serum creatinine levels (SCr) several times a day. In addition, it is recommended to treat electrolyte disturbances, discontinue or dose-adjust nephrotoxic drugs, and dose-adjust drugs with renal elimination.

There are approx. 30+ key companies developing therapies for Acute Kidney Injury. Currently, GUARD THERAPEUTICS is leading the therapeutics market with its Acute Kidney Injury drug candidates in the most advanced stage of clinical development.

Robust pipeline with a novel mechanism of action and increasing incidence are major market drivers for the AKI market growth. Additionally, the AKI pipeline is also expected to change the current dynamics of the market, which presently comprises biologics and molecules with new mechanisms of action like RMC-035, OCE-205, bRESCAP, and others.

Acute Kidney Injury Companies Actively Working in the Therapeutic Market Include:

GUARD THERAPEUTICS, Rénibus Therapeutics, Sentien Biotechnologies, Angion Biomedica, Quark-Pharmaceuticals, AM-Pharma Holding, Metro International Biotech, LLC, MediBeacon, Arch Biopartners Inc., Ocelot Bio, Inc, Pharming Technologies B.V., Vifor Pharma, Mission Therapeutics, XORTX Therapeutics, Ampio Pharmaceuticals Inc., Sulfateq BV, Atorvia, EBI Exponential Biotherapies, Serpin Pharma, CalciMedica Inc., ILIAS Biologics Inc., Arch Biopartners Inc., and many others.

Emerging and Marketed Acute Kidney Injury Drugs Covered in the Report Include:


  • RBT-1: Rénibus Therapeutics

And Many More

Request the Sample PDF to Get a Better Understanding of the Emerging Drugs and Acute Kidney Injury Companies Working in the Market @

Analysis of Emerging Acute Kidney Injury Therapies by Phases

The report covers the emerging products under different phases of clinical development like –

  • Late-stage products (Phase III)

  • Mid-stage products (Phase II)

  • Early-stage product (Phase I) 

  • Pre-clinical and Discovery stage candidates

  • Discontinued and inactive candidates

Route of Administration

Acute Kidney Injury pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as

  • Inhalation

  • Inhalation/Intravenous/Oral

  • Intranasal

  • Intravenous

  • Intravenous/ Subcutaneous

  • Oral

  • Oral/intranasal/subcutaneous

  • Parenteral

  • Subcutaneous

Molecule Type

Products have been categorized under various Molecule types such as

  • Antibody

  • Antisense oligonucleotides

  • Immunotherapy

  • Monoclonal antibody

  • Peptides

  • Protein

  • Recombinant protein

  • Small molecule

  • Stem Cell

  • Vaccine

Learn How the Acute Kidney Injury Treatment Outlook will Evolve with the Ongoing Clinical and commercial Activities in the Therapeutic Market @

Table of Content (TOC)

1. Report Introduction

2. Executive Summary

3. Acute Kidney Injury Treatment Patterns

4. Acute Kidney Injury – DelveInsight’s Analytical Perspective

5. Therapeutic Assessment

6. Acute Kidney Injury Late Stage Products (Phase-III)

7. Acute Kidney Injury Mid-Stage Products (Phase-II)

8. Acute Kidney Injury Early Stage Products (Phase-I)

9. Pre-clinical Products and Discovery Stage Products

10. Inactive Products

11. Dormant Products

12. Acute Kidney Injury Discontinued Products

13. Acute Kidney Injury Product Profiles

14. Major Acute Kidney Injury Companies in the Market

15. Key Products in the Acute Kidney Injury Therapeutics Segment

16. Dormant and Discontinued Products

17. Acute Kidney Injury Unmet Needs

18. Acute Kidney Injury Future Perspectives

19. Acute Kidney Injury Analyst Review  

20. Appendix

21. Report Methodology

*The Table of Contents (TOC) is not exhaustive; the final content may vary. Refer to the sample report for the complete table of contents.

Download Sample PDF to Explore the Key Offerings of the Report @



About DelveInsight

DelveInsight is a leading Business Consultant and Market Research Firm focused exclusively on life sciences. It supports pharma companies by providing comprehensive end-to-end solutions to improve their performance.

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