DelveInsight’s, “Spleen Tyrosine Kinase (SYK) Inhibitors Pipeline Insight, 2025,” report provides comprehensive insights about 10+ companies and 10+ pipeline drugs in Spleen Tyrosine Kinase (SYK) Inhibitors pipeline landscape. It covers the SYK Inhibitor pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
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Key Takeaways from the SYK Inhibitor Pipeline Report
- DelveInsight’s SYK Inhibitor pipeline report depicts a robust space with 10+ active players working to develop 10+ pipeline therapies for SYK Inhibitor treatment.
- The leading SYK Inhibitor Companies such as Genosco, Portola Pharmaceuticals, GlaxoSmithKline, FUJIFILM Corporation, TopiVert, Takeda Oncology, Asana BioSciences and others.
- Promising SYK Inhibitor Pipeline Therapies such as SKI-O-703, Entospletinib and others.
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SYK Inhibitor Emerging Drugs Profile
- Cevidoplenib dimesylate: Genosco
The dimesylate salt of cevidoplenib, an orally available inhibitor of spleen tyrosine kinase (SYK), with potential anti-inflammatory and immunomodulating activities. Upon oral administration, cevidoplenib binds to and inhibits the activity of SYK, blocking Fc receptor and B-cell receptor (BCR)-mediated signaling in inflammatory cells, including macrophages, neutrophils, mast cells, natural killer (NK) cells and B cells. This leads to the inhibition of the activation of these inflammatory cells, and the related inflammatory responses and tissue damage.
- HMPL-523: Hutchison MediPharma
An orally available inhibitor of spleen tyrosine kinase (Syk), with potential immune-modulating and antineoplastic activities. Upon oral administration of Syk inhibitor HMPL-523, this agent binds to and inhibits the activity of Syk. This inhibits B-cell receptor (BCR) signaling, which leads to the inhibition of B-cell activation, and prevents tumor cell activation, migration, adhesion and proliferation.
The SYK Inhibitor Pipeline Report provides insights into
- The report provides detailed insights about companies that are developing therapies for the treatment of SYK Inhibitor with aggregate therapies developed by each company for the same.
- It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for SYK Inhibitor Treatment.
- SYK Inhibitor Companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
- SYK Inhibitor Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.
- Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the SYK Inhibitor market.
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SYK Inhibitor Companies
Genosco, Portola Pharmaceuticals, GlaxoSmithKline, FUJIFILM Corporation, TopiVert, Takeda Oncology, Asana BioSciences and others.
Spleen Tyrosine Kinase (SYK) Inhibitors pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
- Oral
- Intravenous
- Molecule Type
SYK Inhibitor Products have been categorized under various Molecule types such as
- Monoclonal antibodies
- Small molecules
- Product Type
Stay informed about how we’re transforming the future of SYK landscape @ SYK Inhibitor Market Drivers and Barriers, and Future Perspectives
Scope of the SYK Inhibitor Pipeline Report
- Coverage- Global
- SYK Inhibitor Companies- Genosco, Portola Pharmaceuticals, GlaxoSmithKline, FUJIFILM Corporation, TopiVert, Takeda Oncology, Asana BioSciences and others.
- SYK Inhibitor Pipeline Therapies- SKI-O-703, Entospletinib and others.
- SYK Inhibitor Therapeutic Assessment by Product Type: Mono, Combination, Mono/Combination
- SYK Inhibitor Therapeutic Assessment by Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III
For a detailed overview of our latest research findings and future plans, read the full details of SYK Inhibitor Pipeline on our website @ SYK Inhibitor Emerging Drugs and Companies
Table of Content
- Introduction
- Executive Summary
- Spleen Tyrosine Kinase (SYK) Inhibitors: Overview
- Pipeline Therapeutics
- Therapeutic Assessment
- Spleen Tyrosine Kinase (SYK) Inhibitors – DelveInsight’s Analytical Perspective
- In-depth Commercial Assessment
- Spleen Tyrosine Kinase (SYK) Inhibitors Collaboration Deals
- Late Stage Products (Phase II/III)
- TOP 1630: TopiVert
- Mid Stage Products (Phase II)
- Cevidoplenib: Genosco
- PRT 2761: Portola Pharmaceuticals
- Early Stage Products (Phase I/II)
- Gusacitinib: Asana BioSciences
- Early Stage Products (Phase I)
- Mivavotinib: Takeda Oncology
- Pre-clinical and Discovery Stage Products
- Research programme: small molecule therapeutics: Genosco
- Inactive Products
- Comparative Analysis
- Spleen Tyrosine Kinase (SYK) Inhibitors- Market Drivers and Barriers
- Appendix
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