DelveInsight reports that over eight key companies are actively involved in developing more than eight treatment therapies for Palmoplantar Pustulosis.
Palmoplantar Pustulosis Overview:
Palmoplantar pustulosis (PPP) is a rare and chronic inflammatory skin condition marked by the formation of sterile pustules—small to large blisters filled with yellowish, cloudy fluid—on the palms of the hands and/or soles of the feet. These pustules can be painful and often produce a burning sensation. The precise cause of PPP is not fully understood, but potential triggers may include smoking, bacterial infections (such as chronic tonsillitis, sinusitis, or dental issues), contact allergies (especially to metals), and certain medications. Common signs include red and tender skin, pustules, itching, pain, cracked or thickened skin, dry patches, and flaking. Although there is currently no cure, treatment options aim to alleviate symptoms and improve quality of life.
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“Palmoplantar Pustulosis Pipeline Insight 2025” report by DelveInsight provides a comprehensive analysis of the ongoing clinical development activities and growth prospects across the Palmoplantar Pustulosis Therapeutics Market.
Key Takeaways from the Palmoplantar Pustulosis Pipeline Report
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DelveInsight’s Palmoplantar Pustulosis (PPP) pipeline report highlights a dynamic and evolving landscape, with over 8 key companies actively developing more than 8 potential therapies for PPP treatment.
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Notable companies such as Kyowa Kirin Co., Ltd., Aristea Therapeutics Inc., AnaptysBio, Inc., Boehringer Ingelheim, and Janssen Biotech are leading efforts to advance innovative treatment options.
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Prominent therapies under development include KHK4827 (Brodalumab), Imsidolimab, and others, which are progressing through various stages of clinical trials.
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While Spesolimab—an anti-IL-36 receptor antibody—received FDA approval in March 2025 for managing flares in generalized pustular psoriasis (GPP) patients aged 12 and above, it did not demonstrate significant efficacy in a clinical trial targeting PPP, failing to meet its primary endpoint.
Palmoplantar Pustulosis Pipeline Analysis
The report provides insights into:
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The report provides detailed insights into the key companies that are developing therapies in the Palmoplantar Pustulosis Market.
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The report also evaluates different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Palmoplantar Pustulosis treatment.
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It analyzes the key companies involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
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It navigates the emerging drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.
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Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement, and financing details for future advancement of the Palmoplantar Pustulosis market.
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Palmoplantar Pustulosis Emerging Drugs
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KHK4827 (Brodalumab): Kyowa Kirin Co. Ltd.
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Imsidolimab: AnaptysBio, INC.
Palmoplantar Pustulosis Companies
Approximately eight or more major companies are actively engaged in developing treatments for Palmoplantar Pustulosis. Among them, Kyowa Kirin Co., Ltd. has a drug candidate that has reached the most advanced stage of development—Phase III clinical trials.
DelveInsight’s report covers around 8+ products under different phases of clinical development like
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Late stage products (Phase III)
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Mid-stage products (Phase II)
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Early-stage product (Phase I) along with the details of
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Pre-clinical and Discovery stage candidates
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Discontinued & Inactive candidates
Palmoplantar Pustulosis pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
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Intravenous
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Subcutaneous
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Oral
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Intramuscular
Palmoplantar Pustulosis Products have been categorized under various Molecule types such as
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Monoclonal antibody
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Small molecule
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Peptide
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Palmoplantar Pustulosis Pipeline Therapeutic Assessment
• Palmoplantar Pustulosis Assessment by Product Type
• Palmoplantar Pustulosis By Stage
• Palmoplantar Pustulosis Assessment by Route of Administration
• Palmoplantar Pustulosis Assessment by Molecule Type
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Table of Content
1. Report Introduction
2. Executive Summary
3. Palmoplantar Pustulosis Current Treatment Patterns
4. Palmoplantar Pustulosis – DelveInsight’s Analytical Perspective
5. Therapeutic Assessment
6. Palmoplantar Pustulosis Late-Stage Products (Phase-III)
7. Palmoplantar Pustulosis Mid-Stage Products (Phase-II)
8. Early Stage Products (Phase-I)
9. Pre-clinical Products and Discovery Stage Products
10. Inactive Products
11. Dormant Products
12. Palmoplantar Pustulosis Discontinued Products
13. Palmoplantar Pustulosis Product Profiles
14. Palmoplantar Pustulosis Key Companies
15. Palmoplantar Pustulosis Key Products
16. Dormant and Discontinued Products
17. Palmoplantar Pustulosis Unmet Needs
18. Palmoplantar Pustulosis Future Perspectives
19. Palmoplantar Pustulosis Analyst Review
20. Appendix
21. Report Methodology
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