2. Sources in the Food<\/p>\n
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- Mushrooms: Golden Oyster mushrooms<\/a> (2.2–3.94 mg\/g dry weight), shiitake (1.2–2.5 mg\/g), and porcini (up to 7.27 mg\/g) are the most abundant dietary sources .<\/li>\n
- Grains and Legumes: Oats, barley, black beans, and kidney beans contain moderate levels of EGT (0.1–0.5 mg\/g).<\/li>\n
- Animal Products: Organ meats (liver, kidney) and red meat provide EGT derived from microbial synthesis in animal feed.<\/li>\n
- Fermented Foods: Certain fermented products, such as tempeh and miso, may contain trace amounts of EGT from microbial activity<\/li>\n<\/ul>\n
Health Benefits and Mechanisms of Action • Antioxidant and Anti-Inflammatory EffectsErgothioneine scavenges reactive oxygen species (ROS) and reactive nitrogen species (RNS), including hydroxyl radicals (·OH) and peroxynitrite (ONOO\u207b), with higher efficiency than glutathione and vitamin E. It also inhibits pro-inflammatory cytokines like TNF-α and IL-6.• Mitochondrial ProtectionErgothioneine accumulates in mitochondria, where it protects mitochondrial DNA (mtDNA) from oxidative damage and enhances ATP production. Studies in mice showed a 21% increase in lifespan and reduced age-related mitochondrial dysfunction .• Neuroprotective PropertiesEGT crosses the blood-brain barrier and protects neurons from oxidative stress, potentially slowing the progression of Alzheimer’s and Parkinson’s diseases .• ImmunomodulationEGT supports immune cell function by enhancing macrophage phagocytosis and T-cell activation. Application of Ergothioneine<\/p>\n
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- Dietary Supplements: GRAS-approved EGT powders for anti-aging and mitochondrial support.<\/li>\n
- Cosmetics: Topical formulations for UV protection and skin rejuvenation (e.g., Estée Lauder’s Advanced Night Repair).<\/li>\n
- Pharmaceuticals: Clinical trials for neurodegenerative diseases and cardiovascular protection.<\/li>\n<\/ul>\n
Where to Buy Natural Ergothioneine? For high-quality natural ergothioneine powder, contact Xi’an Sost Biotech<\/a>, a leading manufacturer specializing in microbial fermentation and purification technologies. Their products include:<\/p>\n
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- Food Grade Ergothioneine powder: Ideal for dietary supplements and functional foods.<\/li>\n
- Cosmetic Grade Ergothioneine powder: Used in anti-aging creams and sunscreens.<\/li>\n<\/ul>\n
Contact Information:<\/p>\n
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- Website: www.sostapi.com<\/li>\n
- Email: ericyang@xasost.com<\/li>\n<\/ul>\n
Media Contact<\/span>
Company Name:<\/strong> SOST BIOTECH<\/a>
Email:<\/strong> Send Email<\/a>
Country:<\/strong> China
Website:<\/strong> https:\/\/www.sostapi.com\/<\/a><\/p>\n<\/p>\n","protected":false},"excerpt":{"rendered":"
1. Microbial Biosynthesis: The Primary OriginErgothioneine is predominantly synthesized by microorganisms, including fungi, bacteria, and cyanobacteria. Its biosynthesis pathway involves the condensation of L-histidine and L-cysteine, catalyzed by specific enzymes such as EgtB and EgtA . For example: Fungi: Mushrooms, … Continue reading