SHIRLEY, NY, UNITED STATES – May 22, 2019 – CD Genomics, an expert in transcriptomics and next generation sequencing company, announces the technical escalation of its sequencing services, The updated or newly-developed service ranges include three: nanopore sequencing, mitochondrial genome sequencing, and whole plasmid sequencing, which are based on some of the most powerful platforms in this field with unrivaled accuracy and sensitivity.
Nanopore technology for biomolecular sequencing has a wide range of applications in life sciences, including identification of pathogens, food safety monitoring, genomic analysis, metagenomic environmental monitoring, and characterization of bacterial antibiotic resistance. The Nanopore sequencer has been proven to be compatible with a variety of input materials such as genomic DNA, amplified DNA, cDNA and RNA. The nanopore sequencing has some outstanding advantages over traditional workflows. For high molecular weight DNA (HMW-DNA) samples, ultra-long reads of several hundred kb can be sequenced in a single continuous reading. Nanopore sequencing data significantly improved de novo genome assembly and structural genomic variation and transcriptome studies.
Nanopores are nanoscale pores that form a transmembrane gateway in nature. The nanopore delivers ion current through the nanopore and measures the change in current. Information about current changes can be used to identify the molecule. It directly sequences the natural chain of interest without optics or amplification. Different types of library preparation protocols allow for direct DNA/RNA sequencing using epigenetic information. Real-time streaming of sequence data provides quick insight into samples, on-demand sequencing and dynamic workflow. CD genomics provides nanopore sequencing service. PromethION can use up to 48 flow cells on demand – up to 100Gb of sequencing data per flow cell.
Mitochondria play a very important role in important cellular functions. In addition to producing more than 90% of energy required by a cell, mitochondria also produce reactive oxygen species (ROS) and are involved in apoptosis and other important cellular functions. Mutant mtDNA and wild type can coexist as heterogeneity and cause human diseases including cancer, heart disease, diabetes, Alzheimer’s disease, Parkinson’s disease and hypertension. Mitochondrial DNA sequencing is a useful tool for studying human disease research and can also be used for population genetics and biodiversity assessment. CD Genomics offers cost-effective mitochondrial DNA sequencing solutions that can help you achieve high sensitivity, specificity and accuracy to determine mtDNA mutations and heterogeneity levels.
Plasmids are considered to be mobile genetic elements that exist extra-chromosomes and occasionally carry accessory genes that confer host advantages in their niche. Despite their importance, technical barriers still limit plasmid research. Whole plasmid sequencing is rapidly becoming the standard method to increase our understanding of the genetic diversity and evolutionary history of plasmids. Not only does it help define the molecular events that occur during the evolution of these plasmids, but it also provides a more comprehensive overview of the large number of helper genes encoded on the plasmid. CD Genomics’ plasmid sequencing service uses the functionality of the Illumina platform for plasmid validation and has developed a low-cost, high-throughput method for larger-scale plasmid sequencing using PacBio SMRT technology.
“CD Genomics concentrates on supplying the high-quality services and products for labs and research institutes. We guarantee the developed products and services, which are customized, can meet the demands of our clients, who believe in our scientists and CD Genomics”, said Dr. David.
About CD Genomics
CD Genomics is a world-leading genomics services company that innovates sequencing services, as well as genotyping, library construction, bioinformatics, aptamers, microarray, health diagnostics, mutagenesis analyses and others for the genomics industry.
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Company Name: CD Genomics
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Website: https://www.cd-genomics.com/